FLRT1

Fibronectin leucine rich transmembrane protein 1 is a protein that in humans is encoded by the FLRT1 gene. [5]

FLRT1
Identifiers
AliasesFLRT1, SPG68, fibronectin leucine rich transmembrane protein 1
External IDsOMIM: 604806 MGI: 3026647 HomoloGene: 40864 GeneCards: FLRT1
Orthologs
SpeciesHumanMouse
Entrez

23769

396184

Ensembl

ENSG00000126500

ENSMUSG00000047787

UniProt

Q9NZU1

Q6RKD8

RefSeq (mRNA)

NM_013280
NM_001384466

NM_201411

RefSeq (protein)

NP_037412

NP_958813

Location (UCSC)Chr 11: 64.04 – 64.12 MbChr 19: 7.07 – 7.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in the kidney and brain.

References

  1. GRCh38: Ensembl release 89: ENSG00000126500 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000047787 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Fibronectin leucine rich transmembrane protein 1". Retrieved 2017-05-30.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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