Fabiana (plant)

Members of the genus grow within 16◦ and 51◦ latitude in the arid mountainous regions of South America between 1000–4900 m above sea level.[2]

The genus Fabiana has been studied by ethnopharmacologists due to the use of extracts from species within the genus in traditional South American medicine. The plants are employed as an antiseptic, anti-inflammatory (through infusions and decoctions), as well as to set broken bones, using the resin exuded by the foliage and branches. European researchers have periodically studied the medicinal value of the plant since as early as 1877.[3] A range of current studies have validated the diuretic and anti-inflammatory, and anti-oxidant for Fabiana species including F. imbricata F. patagonica, F. punnensis, F. densa, and particularly, F. bryoides, which also inhibited spontaneous mutanogenisis in the bacterium Salmonella typhimumrium by up to 50% with no impact on cell viability.[2][4] The foliage of F. imbricata, specifically has been traditionally employed as a diueretic and digestive and has been proven to have a dose-dependent gastroprotective effect, in studies evaluating the main sesquiterpene of the foliage.[4] Interest in F. imbricata has extended into the development of invitro culturing of the plant’s tissue for the harvesting of secondary metabolites for further research.[5]

The proposed number of species included in the genus Fabiana ranges significantly from 15 [2] to 36.[6] As of 2013 the USDA lists only the single type species within the genus in 2013. The USDA’s listing indicates lack of commercial interest in the genus, rather than any scientific consensus of species number.[7]

While the family Solanaceae has been well studied and documented overall, this research attention has not been applied uniformly amongst the genera. Genera such as Fabiana, with limited commercial or cultural agricultural value have been overlooked in detailed phylogenetic analysis.