Ferlavirus
Ferlavirus, also referred to as Ophidian paramyxovirus, is a genus of viruses in the family Paramyxoviridae, order Mononegavirales.[2][3] Reptiles serve as natural hosts. There is currently only one species in this genus (Reptilian ferlavirus) to accommodate a single virus, Fer-de-Lance virus (FDLV).[4]
| Reptilian ferlavirus | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Monjiviricetes |
| Order: | Mononegavirales |
| Family: | Paramyxoviridae |
| Subfamily: | Orthoparamyxovirinae |
| Genus: | Ferlavirus |
| Species: | Reptilian ferlavirus |
| Synonyms[1] | |
|
Fer-de-Lance paramyxovirus | |
Structure
Ferlaviruses produce virions that are enveloped, with spherical geometries. The virion diameter is around 150 nm. Ferlavirus genome is linear and around 15 kb in length. The genome codes for 8 proteins.[5]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Ferlavirus | Spherical | Enveloped | Linear | Monopartite |
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus exits the host cell by budding. Reptiles serve as the natural host.[5]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Ferlavirus | Unknown | None | Glycoprotein | Budding | Cytoplasm | Cytoplasm | Unknown |
References
- Rima, Bertus K.; et al. (18 July 2016). "Implementation of taxon-wide non-Latinized binomial species names in the family Paramyxoviridae" (PDF). International Committee on Taxonomy of Viruses (ICTV). Retrieved 28 August 2019.
- Rima, B; Balkema-Buschmann, A; Dundon, WG; Duprex, WP; Easton, A; Fouchier, R; Kurath, G; Lamb, R; Lee, B; Rota, P; Wang, L; ICTV Report Consortium (December 2019). "ICTV Virus Taxonomy Profile: Paramyxoviridae". The Journal of General Virology. 100 (12): 1593–1594. doi:10.1099/jgv.0.001328. PMC 7273325. PMID 31609197.
- "ICTV Report Paramyxoviridae".
- Amarasinghe, Gaya K.; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Beer, Martin; Bejerman, Nicolás; Blasdell, Kim R.; Bochnowski, Alisa; Briese, Thomas (7 April 2017). "Taxonomy of the order Mononegavirales: update 2017". Archives of Virology. 162 (8): 2493–2504. doi:10.1007/s00705-017-3311-7. ISSN 1432-8798. PMC 5831667. PMID 28389807.
- "Viral Zone". ExPASy. Retrieved 13 August 2015.