Glycolate dehydrogenase

In enzymology, a glycolate dehydrogenase (EC 1.1.99.14) is an enzyme that catalyzes the chemical reaction

glycolate + acceptor glyoxylate + reduced acceptor
glycolate dehydrogenase
Identifiers
EC no.1.1.99.14
CAS no.37368-32-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Thus, the two substrates of this enzyme are glycolate and acceptor, whereas its two products are glyoxylate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is glycolate:acceptor 2-oxidoreductase. Other names in common use include glycolate oxidoreductase, glycolic acid dehydrogenase, and glycolate:(acceptor) 2-oxidoreductase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

    • Lord JM (May 1972). "Glycolate oxidoreductase in Escherichia coli". Biochimica et Biophysica Acta (BBA) - Bioenergetics. 267 (2): 227–37. doi:10.1016/0005-2728(72)90111-9. PMID 4557653.


    This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.