Goodell's sign

In medicine, Goodell's sign is an indication of pregnancy. It is a significant softening of the vaginal portion of the cervix from increased vascularization. This vascularization is a result of hypertrophy and engorgement of the vessels below the growing uterus. This sign occurs at approximately six weeks' gestation.

The sign is named after William Goodell (1829–1874).

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