HFE
HFE may refer to:
- HFE (gene), a gene that encodes the Human hemochromatosis protein
- H-parameter model (hFE), the current gain of a bipolar junction transistor
- Health First Europe
- Hefei Luogang International Airport, in Anhui, China, now defunct
- Hefei Xinqiao International Airport, in Anhui, China
- Hello from Earth, an interstellar radio message
- Herschend Family Entertainment Corporation, an American entertainment company
- Hertford East railway station, in England
- Hidden Field Equations, a cryptosystem
- Horizontal Fiscal Equalisation, in Australia
- Human factors engineering
- Hydrofluoroether, a solvent
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