Heterosubtypic immunity

"Heterosubtypic immunity (HSI) is defined as cross-protection to infection with an influenza A virus serotype other than the one used for primary infection."[1] In layman's terms: an 'infection with "seasonal" influenza A viruses could induce immunity against unrelated sub-strains.'[2]

References
  1. Huan H. Nguyen et al, Heterosubtypic Immunity to Influenza A Virus Infection Requires a Properly Diversified Antibody Repertoire, Journal of Virology
  2. Leicester Mercury Winter flu could help protect kids, 30 October 2009
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