Hydroxypyruvate decarboxylase

The enzyme hydroxypyruvate decarboxylase (EC 4.1.1.40) catalyzes the chemical reaction

hydroxypyruvate glycolaldehyde + CO2
hydroxypyruvate decarboxylase
Identifiers
EC no.4.1.1.40
CAS no.37289-43-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is hydroxypyruvate carboxy-lyase (glycolaldehyde-forming). This enzyme is also called hydroxypyruvate carboxy-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

    • HEDRICK JL, SALLACH HJ (1964). "THE NONOXIDATIVE DECARBOXYLATION OF HYDROXYPYRUVATE IN MAMMALIAN SYSTEMS". Arch. Biochem. Biophys. 105 (2): 261–9. doi:10.1016/0003-9861(64)90007-4. PMID 14186730.


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