IGFBP5

Insulin-like growth factor-binding protein 5 (IBF-5) is a protein that in humans is encoded by the IGFBP5 gene.[5] An IGFBP5 gene was recently identified as being important for adaptation to varying water salinity in fish.[6]

IGFBP5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIGFBP5, IBP5, insulin like growth factor binding protein 5
External IDsOMIM: 146734 MGI: 96440 HomoloGene: 56489 GeneCards: IGFBP5
Orthologs
SpeciesHumanMouse
Entrez

3488

16011

Ensembl

ENSG00000115461

ENSMUSG00000026185

UniProt

P24593

Q07079

RefSeq (mRNA)

NM_000599

NM_010518

RefSeq (protein)

NP_000590

NP_034648

Location (UCSC)Chr 2: 216.67 – 216.7 MbChr 1: 72.9 – 72.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000115461 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026185 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Allander SV, Larsson C, Ehrenborg E, Suwanichkul A, Weber G, Morris SL, Bajalica S, Kiefer MC, Luthman H, Powell DR (May 1994). "Characterization of the chromosomal gene and promoter for human insulin-like growth factor binding protein-5". J Biol Chem. 269 (14): 10891–8. doi:10.1016/S0021-9258(17)34142-X. PMID 7511611.
  6. Kusakabe M, Ishikawa A, Ravinet M, Yoshida K, Makino T, Toyoda A, Fujiyama A, Kitano J (2017). "Genetic basis for variation in salinity tolerance between stickleback ecotypes". Molecular Ecology. 26 (1): 304–319. doi:10.1111/mec.13875. PMID 27706866. S2CID 7821799.

Further reading


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