Interleukin-15 receptor
Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha subunit and shares common beta and gamma subunits with the IL-2 receptor.[1]
| interleukin 15 receptor, alpha | |||||||
|---|---|---|---|---|---|---|---|
 | |||||||
| Identifiers | |||||||
| Symbol | IL15RA | ||||||
| NCBI gene | 3601 | ||||||
| HGNC | 5978 | ||||||
| OMIM | 601070 | ||||||
| RefSeq | NM_172200 | ||||||
| UniProt | Q13261 | ||||||
| Other data | |||||||
| Locus | Chr. 10 p15-10p14 | ||||||
| |||||||
| interleukin 2 receptor, beta | |||||||
|---|---|---|---|---|---|---|---|
 | |||||||
| Identifiers | |||||||
| Symbol | IL2RB | ||||||
| Alt. symbols | CD122 | ||||||
| NCBI gene | 3560 | ||||||
| HGNC | 6009 | ||||||
| OMIM | 146710 | ||||||
| RefSeq | NM_000878 | ||||||
| UniProt | P14784 | ||||||
| Other data | |||||||
| Locus | Chr. 22 q13 | ||||||
| |||||||
| interleukin 2 receptor, gamma (severe combined immunodeficiency) | |
|---|---|
 | |
| Identifiers | |
| Symbol | IL2RG |
| Alt. symbols | SCIDX1, IMD4 |
| NCBI gene | 3561 |
| HGNC | 6010 |
| OMIM | 308380 |
| RefSeq | NM_000206 |
| Other data | |
| Locus | Chr. X q13 |
References
- Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA (1995). "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. Biol. Chem. 270 (50): 29862–9. doi:10.1074/jbc.270.50.29862. PMID 8530383.
External links
- Receptors,+Interleukin-15 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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