Jan Löwe

Jan Löwe FRS (born 14 July 1967)[2] is a German molecular and structural biologist and the Director of the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) in Cambridge, UK. He became Director of the MRC-LMB in April 2018,[3] succeeding Sir Hugh Pelham. Löwe is known for his contributions to the current understanding of bacterial cytoskeletons.[4][5][1]

Professor Jan Löwe
FRS
Director of the MRC-LMB
Assumed office
2018
Preceded bySir Hugh Pelham
Personal details
Born (1967-07-14) 14 July 1967
NationalityGerman
Alma mater
Known forStructural biology of bacterial cytoskeletons
AwardsEMBO Member (2004)
EMBO Gold Medal (2007)
Scientific career
Fields
Institutions
ThesisCrystal structure of the 20S proteasome from T. acidophilum (1995)
Doctoral advisorRobert Huber
Websitewww2.mrc-lmb.cam.ac.uk/groups/jyl

Education

Löwe was awarded a Diploma in Chemistry by the University of Hamburg in 1992.[2] He was then awarded his Dr. rer. nat. in 1995 by the Technische Universität München, for his thesis work on the structure of the proteasome[6] completed at the Max Planck Institute of Biochemistry under the supervision of Robert Huber.[2]

Career and research

Löwe worked briefly as a postdoctoral researcher at the Max Planck Institute of Biochemistry,[7] before moving to MRC-LMB in 1996 to take up an EMBO long-term fellowship to work on crystallising FtsZ, a bacterial homologue of eukaryotic tubulin, with Linda A. Amos.[8] Löwe became a group leader at MRC-LMB in 1998 and was awarded tenure in 2002.[2] His group has largely worked on the structural and molecular biology of prokaryotic cytoskeletons, but has also made important contributions to the current understanding of cell division and DNA partitioning in both prokaryotes and eukaryotes.[4] Löwe became the Director of MRC-LMB in April 2018,[3] having formerly been Deputy Director (2016-18) and Joint Head of the Structural Studies Division at the institute (2010-18).[2] In 2018, the title of Honorary Professor of Structural and Molecular Microbiology at the University of Cambridge was conferred on him.[9]

Awards and honours

References
  1. Jan Löwe publications indexed by Google Scholar
  2. Anon (2017). "Löwe, Jan". Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.255866. (Subscription or UK public library membership required.)
  3. Brackley, Paul (14 February 2018). "Dr Jan Löwe says he's 'humbled' to take over as director of MRC Laboratory of Molecular Biology". Cambridge Independent. No. Online. Retrieved 27 April 2018.
  4. Anon (2008). "Dr Jan Löwe FRS". royalsociety.org. London: Royal Society. Retrieved 30 April 2018. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
  5. Jan Löwe publications from Europe PubMed Central
  6. Lowe, J; Stock, D; Jap, B; Zwickl, P; Baumeister, W; Huber, R (1995). "Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution". Science. 268 (5210): 533–539. Bibcode:1995Sci...268..533L. doi:10.1126/science.7725097. PMID 7725097. closed access
  7. "Jan Löwe CV" (PDF). www.leopoldina.org. Retrieved 30 April 2018.
  8. Löwe, Jan; Amos, Linda A. (1998). "Crystal structure of the bacterial cell-division protein FtsZ". Nature. 391 (6663): 203–206. Bibcode:1998Natur.391..203L. doi:10.1038/34472. PMID 9428770. S2CID 4330857. closed access
  9. Cambridge University Reporter CXLIX No 6519, 26 September 2018
  10. "EMBO profile". people.embo.org. Retrieved 30 April 2018.
  11. "Gold medal announcement". EMBO. Retrieved 30 April 2018.
  12. "List of Members". www.leopoldina.org. Retrieved 30 April 2018.

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