Jedi1

Jedi1 (IUPAC name: 2-methyl-5-phenylfuran-3-carboxylic acid) is a chemical compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception.[1][2]

Jedi1
Names
Preferred IUPAC name
2-methyl-5-phenylfuran-3-carboxylic acid
Identifiers
3D model (JSmol)
  • InChI=1S/C12H10O3/c1-8-10(12(13)14)7-11(15-8)9-5-3-2-4-6-9/h2-7H,1H3,(H,13,14)
    Key: VLMNACSEESRUAK-UHFFFAOYSA-N
  • CC1=C(C=C(O1)C2=CC=CC=C2)C(=O)O
Properties
C12H10O3
Molar mass 202.209 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References
  1. Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, et al. (April 2018). "A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel". Nature Communications. 9 (1): 1300. doi:10.1038/s41467-018-03570-9. PMC 5880808. PMID 29610524.
  2. Fang XZ, Zhou T, Xu JQ, Wang YX, Sun MM, He YJ, Pan SW, Xiong W, Peng ZK, Gao XH, Shang Y (January 2021). "Structure, kinetic properties and biological function of mechanosensitive Piezo channels". Cell & Bioscience. 11 (1): 13. doi:10.1186/s13578-020-00522-z. PMC 7796548. PMID 33422128.
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