Jon A. Wolff

Jon Asher Wolff (September 25, 1956 – April 17, 2020) was an American geneticist. He was the lead author on a 1990 study published in the journal Science that first suggested the possibility of synthesizing mRNA in a laboratory to trigger the production of a desired protein.[1][2] As of 2021, the article has been cited in the scholarly press more than 630 times and been described, by Nature, as "the first step toward making a vaccine from mRNA".[3][4]

Wolff was born in Bayside, Queens, New York, in 1956,[5][6] received his undergraduate education at Cornell University and earned an MD from Johns Hopkins University.[7] He was a professor of medicine at the University of Wisconsin and later founder of the biotechnology firm Mirus Bio.[3] He died in Denver, Colorado, from esophageal cancer at age 63.[5]

References
  1. Jon A. Wolff; Robert Malone; Williams P; Chong W; Acsadi G; Jani A; Philip L. Felgner (1 March 1990). "Direct gene transfer into mouse muscle in vivo". Science. 247 (4949 Pt 1): 1465–1468. doi:10.1126/SCIENCE.1690918. ISSN 0036-8075. PMID 1690918. Wikidata Q44656494.
  2. Hecking, Claus (June 23, 2021). "Hopes Are High for the Technology that Is Leading Us Out of the Pandemic". Der Spiegel. Retrieved July 31, 2021.
  3. Jones, Trey (April 15, 2021). "The Lab Report: How former UW physician scientist changed gene therapy forever, inspiring COVID-19 vaccines". Badger Herald. Retrieved July 31, 2021.
  4. May, Mike (May 31, 2021). "After COVID-19 successes, researchers push to develop mRNA vaccines for other diseases". Nature. 27 (6): 930–932. doi:10.1038/s41591-021-01393-8. PMID 34059823.
  5. "Jon Wolff" (PDF). Crested Butte News. May 1, 2020. Retrieved August 4, 2021.
  6. "Wolff, Jon A. (Jon Asher), 1956-". LC Linked Data Service. The Library of Congress. Retrieved 4 August 2021.
  7. "Saying Goodbye to a Colleague and Friend". pediatrics.wisc.edu. University of Wisconsin. Retrieved July 31, 2021.


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