Judi Allen

Judith Elizabeth Allen FRS FMedSci FRSE FRSB is a British scientist who is Professor of Immunobiology at the University of Manchester.[2][3] She is an expert on macrophages activated during helminthiasis and was elected Fellow of the Royal Society (FRS) in 2023.

For The American actress, see Judith Allen.
Judi Allen

FRS FMedSci FRSE FRSB
Born
Judith Elizabeth Allen
Alma materBates College
University of California, Berkeley
AwardsEMBO Member (2018)[1]
Scientific career
InstitutionsUniversity of Manchester
Imperial College London
University of Edinburgh
ThesisThe cysteine-rich proteins of Chlamydia trachomatis in structure and immunity (1991)
Websiteresearch.manchester.ac.uk/en/persons/judi.allen

Early life and education

Allen earned her undergraduate degree at Bates College.[4] She was a doctoral researcher at the University of California, Berkeley,[4] where her PhD investigated cysteine-rich proteins of Chlamydia trachomatis.[5]

Research and career

Allen spent several years in the biotechnology sector before joining Imperial College London as a postdoctoral researcher.[4] In 1997, she was awarded a fellowship from the Medical Research Council and moved to the University of Edinburgh. She was made Professor of Immunobiology there in 2005.[6]

Allen studies helminthiasis, a disease caused by helminth (parasitic worm) infection. The infection is associated with the induction of a type 2 immune response. Allen has identified macrophages with a specific type 2 expression profile, which are found both at the site of the infection and in injured tissue. The macrophage phenotype is influenced by the genotype of the host and the infected site. Allen discovered a relationship between the chitinase-like protein 3 YM1 and Interleukin 17, an inflammatory cytokine associated with autoimmune disease.[7][8]

Allen joined the University of Manchester in 2016.[9]

Awards and honours

Selected publications
  • Peter J. Murray; Judith E. Allen; Subhra K. Biswas; et al. (August 2014). "Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines". Immunity. 41 (2): 339–340. doi:10.1016/J.IMMUNI.2014.07.009. ISSN 1074-7613. Wikidata Q56942151.
  • Stephen J Jenkins; Dominik Ruckerl; Peter C Cook; Lucy H Jones; Fred D Finkelman; Nico van Rooijen; Andrew S MacDonald; Judith E Allen (12 May 2011). "Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation". Science. 332 (6035): 1284–1288. doi:10.1126/SCIENCE.1204351. ISSN 0036-8075. PMC 3128495. PMID 21566158. Wikidata Q35083309.
  • Luke C Davies; Stephen J Jenkins; Judith E Allen; Philip R Taylor (October 2013). "Tissue-resident macrophages". Nature Immunology. 14 (10): 986–95. doi:10.1038/NI.2705. ISSN 1529-2908. PMC 4045180. PMID 24048120. Wikidata Q26991488.

References
  1. "Find people in the EMBO Communities". people.embo.org. Retrieved 2023-05-11.
  2. Judi Allen publications indexed by the Scopus bibliographic database. (subscription required)
  3. Judi Allen publications from Europe PubMed Central
  4. "The DBM welcomes Prof. Judith E. Allen as new Scientific Advisory Board Member for the Immunology Focal Area". biomedizin.unibas.ch. Retrieved 2023-05-11.
  5. Allen, Judith (1991). The cysteine-rich proteins of Chlamydia trachomatis in structure and immunity. berkeley.edu (PhD thesis). University of California, Berkeley. OCLC 25765993.
  6. "Judi Allen". Department of Molecular Biology. Retrieved 2023-05-11.
  7. Sutherland, Tara E.; Rückerl, Dominik; Logan, Nicola; Duncan, Sheelagh; Wynn, Thomas A.; Allen, Judith E. (2018-11-30). "Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection". PLOS Pathogens. 14 (11): e1007423. doi:10.1371/journal.ppat.1007423. ISSN 1553-7374. PMC 6291165. PMID 30500858.
  8. "Judi Allen (Univ of Manchester, UK)". Department of Molecular Biology. Retrieved 2023-05-11.
  9. research.manchester.ac.uk/en/persons/judi.allen
  10. "Professor Judith Allen". rse.org.uk. Royal Society of Edinburgh. Retrieved 2023-05-11.
  11. "Judith E Allen, FRSE, FRSB, FMedSci". International Cytokine & Interferon Society. Retrieved 2023-05-11.
  12. Anon (2023). "Professor Judith Allen FRS". royalsociety.org. London: Royal Society. Retrieved 2023-05-11.
  13. "Professor Judith Allen". acmedsci.ac.uk. Academy of Medical Sciences. Retrieved 2023-05-11.
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