L-arabinitol 2-dehydrogenase
In enzymology, a L-arabinitol 2-dehydrogenase (EC 1.1.1.13) is an enzyme that catalyzes the chemical reaction
- L-arabinitol + NAD+ L-ribulose + NADH + H+
L-arabinitol 2-dehydrogenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.13 | ||||||||
CAS no. | 9028-20-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are L-arabinitol and NAD+, whereas its 3 products are L-ribulose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-arabinitol:NAD+ 2-oxidoreductase (L-ribulose-forming). Other names in common use include L-arabinitol dehydrogenase (ribulose-forming), and L-arabinitol (ribulose-forming) dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.
References
- Chiang C, Knight SG (1961). "L-Arabinose metabolism by cell-free extracts of Penicillium chrysogenum". Biochim. Biophys. Acta. 46 (2): 271–8. doi:10.1016/0006-3002(61)90750-8. PMID 13692999.
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