Coal tar

Coal tar is used in medicated shampoo, soap and ointment. It demonstrates antifungal, anti-inflammatory, anti-itch, and antiparasitic properties.[12] It may be applied topically as a treatment for dandruff and psoriasis, and to kill and repel head lice.[5] It may be used in combination with ultraviolet light therapy.[5]

Coal tar may be used in two forms: crude coal tar (Latin: pix carbonis) or a coal tar solution (Latin: liquor picis carbonis, LPC) also known as liquor carbonis detergens (LCD).[12][13][14] Named brands include Denorex, Balnetar, Psoriasin, Tegrin, T/Gel, and Neutar. When used in the extemporaneous preparation of topical medications, it is supplied in the form of coal tar topical solution USP, which consists of a 20% w/v solution of coal tar in alcohol, with an additional 5% w/v of polysorbate 80 USP; this must then be diluted in an ointment base such as petrolatum.

Coal tar was a component of the first sealed roads. In its original development by Edgar Purnell Hooley, tarmac was tar covered with granite chips. Later the filler used was industrial slag. Today, petroleum derived binders and sealers are more commonly used. These sealers are used to extend the life and reduce maintenance cost associated with asphalt pavements, primarily in asphalt road paving, car parks and walkways.

Coal tar is incorporated into some parking-lot sealcoat products used to protect the structural integrity of the underlying pavement.[15] Sealcoat products that are coal-tar based typically contain 20 to 35 percent coal-tar pitch.[15] Research[16] shows it is used throughout the United States of America, however several areas have banned its use in sealcoat products,[17][18][19] including the District of Columbia; the city of Austin, Texas; Dane County, Wisconsin; the state of Washington; and several municipalities in Minnesota and others.[20][21]

Being flammable, coal tar is sometimes used for heating or to fire boilers. Like most heavy oils, it must be heated before it will flow easily.[22]

A large part of the binder used in the graphite industry for making "green blocks" is coke oven volatiles (COV), a considerable portion of which is coal tar. During the baking process of the green blocks as a part of commercial graphite production, most of the coal tar binders are vaporised and are generally burned in an incinerator to prevent release into the atmosphere, as COV and coal tar can be injurious to health.[23][24]

Coal tar is also used to manufacture paints, synthetic dyes (notably tartrazine/Yellow #5), and photographic materials.[25]

In Ferroalloy industry, coal tar pitch is a main component of the electrode paste used in electric arc furnaces. Coal tar pitch act as the binder for solid filler that can be either coke or calcined anthracite, forming electrode paste, also widely known as Söderberg electrode paste.[26]

In the coal gas era, there were many companies in Britain whose business was to distill coal tar to separate the higher-value fractions, such as naphtha, creosote and pitch. Many industrial chemicals were first isolated from coal tar during this time. These companies included:[27][28]

• Bonnington Chemical Works
• British Tar Products
• Lancashire Tar Distillers
• Midland Tar Distillers
• Newton, Chambers & Company (owners of Izal brand disinfectant)
• Sadlers Chemicals

In modern times, coal tar is mostly traded as fuel and an application for tar, such as roofing. The total value of the trade in coal tar is around US$20 billion each year.[29]

Long-term, consistent exposure to coal tar likely increases the risk of non-melanoma skin cancers.[33] Evidence is inconclusive whether medical coal tar, which does not remain on the skin for the long periods seen in occupational exposure, causes cancer, because there is insufficient data to make a judgment.[34] While coal tar consistently causes cancer in cohorts of workers with chronic occupational exposure, animal models, and mechanistic studies,[35] the data on short-term use as medicine in humans has so far failed to show any consistently significant increase in rates of cancer.[34]

Coal tar contains many polycyclic aromatic hydrocarbons, and it is believed that their metabolites bind to DNA, damaging it.[36] The PAHs found in coal tar and air pollution induce immunosenescence and cytotoxicity in epidermal cells.[37][38] It's possible that the skin can repair itself from this damage after short-term exposure to PAHs but not after long-term exposure.[34] Long-term skin exposure to these compounds can produce "tar warts", which can progress to squamous cell carcinoma.[39]

Coal tar was one of the first chemical substances proven to cause cancer from occupational exposure, during research in 1775 on the cause of chimney sweeps' carcinoma.[39] Modern studies have shown that working with coal tar pitch, such as during the paving of roads or when working on roofs, increases the risk of cancer.[35]

The International Agency for Research on Cancer lists coal tars as Group 1 carcinogens, meaning they directly cause cancer.[35][40][41] The U.S. Department of Health and Human Services lists coal tars as known human carcinogens.[42]

In response to public health concerns regarding the carcinogenicity of PAHs some municipalities, such as the city of Milwaukee, have banned the use of common coal tar-based road and driveway sealants citing concerns of elevated PAH content in groundwater.[43]

Coal tar causes increased sensitivity to sunlight,[44] so skin treated with topical coal tar preparations should be protected from sunlight.

The residue from the distillation of high-temperature coal tar, primarily a complex mixture of three or more membered condensed ring aromatic hydrocarbons, was listed on 13 January 2010 as a substance of very high concern by the European Chemicals Agency.[45]

Exposure to coal tar pitch volatiles can occur in the workplace by breathing, skin contact, or eye contact. The Occupational Safety and Health Administration (OSHA) has set the permissible exposure limit) to 0.2 mg/m³ benzene-soluble fraction over an 8-hour workday. The National Institute for Occupational Safety and Health (NIOSH) has set a recommended exposure limit (REL) of 0.1 mg/m³ cyclohexane-extractable fraction over an 8-hour workday. At levels of 80 mg/m³, coal tar pitch volatiles are immediately dangerous to life and health.[56]

When used as a medication in the United States, coal tar preparations are considered over-the-counter drug pharmaceuticals and are subject to regulation by the Food and Drug Administration (FDA).