MOBKL1A

Mps one binder kinase activator-like 1A, also known as Mob1 homolog 1A, is a protein that in humans is encoded by the MOBKL1A gene.[5][6]

MOB1B
Identifiers
AliasesMOB1B, MATS2, MOB4A, MOBKL1A, MOB kinase activator 1B
External IDsOMIM: 609282 MGI: 1915723 HomoloGene: 61676 GeneCards: MOB1B
Orthologs
SpeciesHumanMouse
Entrez

92597

68473

Ensembl

ENSG00000173542

ENSMUSG00000006262

UniProt

Q7L9L4

Q8BPB0

RefSeq (mRNA)

NM_001244766
NM_001244767
NM_173468

NM_026735

RefSeq (protein)

NP_001231695
NP_001231696
NP_775739

NP_081011

Location (UCSC)Chr 4: 70.9 – 71.02 MbChr 5: 88.87 – 88.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation.[5]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000173542 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000006262 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: MOB1".
  6. Devroe E, Erdjument-Bromage H, Tempst P, Silver PA (June 2004). "Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases". J. Biol. Chem. 279 (23): 24444–51. doi:10.1074/jbc.M401999200. PMID 15067004.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.