Naringenin 7-O-methyltransferase

Naringenin 7-O-methyltransferase (EC 2.1.1.232, NOMT) (full systematic name S-adenosyl-L-methionine:(2S)-5,7,4'-trihydroxyflavanone 7-O-methyltransferase) is a methyltransferase isolated from rice, which catalyzes the biosynthesis of sakuranetin.[1]

Naringenin 7-O-methyltransferase
Identifiers
EC no.2.1.1.232
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme catalyses the following chemical reaction:

S-adenosyl-L-methionine + (2S)-naringenin S-adenosyl-L-homocysteine + (2S)-sakuranetin

While the enzyme is not present in healthy rice leaves, it can be induced by treatment with ultraviolet radiation, jasmonic acid and copper chloride.[1]

References

  1. Rakwal R, Agrawal GK, Yonekura M, Kodama O (June 2000). "Naringenin 7-O-methyltransferase involved in the biosynthesis of the flavanone phytoalexin sakuranetin from rice (Oryza sativa L.)". Plant Science. 155 (2): 213–221. doi:10.1016/s0168-9452(00)00223-5. PMID 10814825.
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