Nuclear groove

A nuclear groove is an invagination of the nuclear envelope, in the longitudinal axis.[1] It can be present in:

Nuclear grooves (arrows indicate one of them) in papillary thyroid cancer. H&E stain.
Cytopathology of papillary thyroid carcinoma, with typical features, with nuclear groove at bottom right. Pap stain.

References

  1. Batistatou, Anna; Scopa, Chrisoula D. (2008). "Review Articles: Pathogenesis and Diagnostic Significance of Nuclear Grooves in Thyroid and Other Sites". International Journal of Surgical Pathology. 17 (2): 107–110. doi:10.1177/1066896908316071. ISSN 1066-8969.
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