OR10A2

OR10A2
Identifiers
Aliases	OR10A2, OR10A2P, OR11-82, OR11-86, OST363, olfactory receptor family 10 subfamily A member 2
External IDs	MGI: 3030548 HomoloGene: 72055 GeneCards: OR10A2
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	6,874,717 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	106,677,009 bp[2]
RNA expression pattern
	Top expressed in
	reproductive system; ; reproductive organ; ; gonad; ; male reproductive system; ; testicle;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	341276
	259035
	ENSG00000170790
	ENSMUSG00000049674
	Q9H208
	Q7TRN0
	NM_001004460
	NM_147033
	NP_001004460
	NP_667244
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor family 10 subfamily A member 2 is a protein that in humans is encoded by the OR10A2 gene. [5]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].

Genetic differences

OR10A2 (as well as OR6A2 which is located near it on chromosome 11) has been proposed as a candidate gene responsible for the genetic portion of the variation in cilantro preference.[6]

References

GRCh38: Ensembl release 89: ENSG00000170790 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000049674 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Olfactory receptor family 10 subfamily A member 2". Retrieved 2020-04-19.
Eriksson N, Wu S, Do CB, Kiefer AK, Tung JY, Mountain JL, Hinds DA, Francke U (29 November 2012). "A genetic variant near olfactory receptor genes influences cilantro preference". Flavour. 1. arXiv:1209.2096. doi:10.1186/2044-7248-1-22. S2CID 199627.

OR10A2

Function

Genetic differences

References

Further reading