L-serine-phosphatidylethanolamine phosphatidyltransferase
L-serine-phosphatidylethanolamine phosphatidyltransferase (EC 2.7.8.29, phosphatidylserine synthase 2, serine-exchange enzyme II, PTDSS2 (gene)) is an enzyme with systematic name L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- L-1-phosphatidylethanolamine + L-serine L-1-phosphatidylserine + ethanolamine
| L-serine-phosphatidylethanolamine phosphatidyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.8.29 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme catalyses replacement of a polar head group of phosphatidylethanolamine with L-serine.
References
- Stone SJ, Vance JE (August 1999). "Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2". The Biochemical Journal. 342 (1): 57–64. doi:10.1042/0264-6021:3420057. PMC 1220436. PMID 10432300.
- Tomohiro S, Kawaguti A, Kawabe Y, Kitada S, Kuge O (March 2009). "Purification and characterization of human phosphatidylserine synthases 1 and 2". The Biochemical Journal. 418 (2): 421–9. doi:10.1042/bj20081597. PMID 19014349.
External links
- L-serine-phosphatidylethanolamine+phosphatidyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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