Phenylpyruvate decarboxylase
The enzyme phenylpyruvate decarboxylase (EC 4.1.1.43) catalyzes the chemical reaction
- phenylpyruvate phenylacetaldehyde + CO2
| phenylpyruvate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.1.1.43 | ||||||||
| CAS no. | 37289-45-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming). This enzyme is also called phenylpyruvate carboxy-lyase. This enzyme participates in phenylalanine and tryptophan metabolism.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2NXW.
References
- Asakawa T, Wada H, Yamano T (1968). "Enzymatic conversion of phenylpyruvate to phenylacetate". Biochim. Biophys. Acta. 170 (2): 375–91. doi:10.1016/0304-4165(68)90017-2. PMID 4303395.
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