Prisca Liberali
Prisca Liberali is an Italian chemist who is a senior group leader at the Friedrich Miescher Institute for Biomedical Research.[1] Her research takes a systems biology approach to understand the behaviour of multi-cellular systems. She was awarded the EMBO Gold Medal and EMBO Membership in 2022.
Prisca Liberali | |
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![]() Liberali presents at the Human Cell Atlas Computational Methods meeting in 2017 | |
Born | |
Alma mater | Mario Negri Institute for Pharmacological Research Sapienza University of Rome Open University (PhD) |
Awards | EMBO Gold Medal (2022) EMBO Member (2022) |
Scientific career | |
Institutions | Friedrich Miescher Institute for Biomedical Research ETH Zurich University of Basel |
Thesis | Mechanisms regulating the dual function of CtBP3/BARS in mammal cell membrane fission and transcription (2008) |
Website | liberalilab |
Early life and education
Liberali was born in Belgium, and grew up between Belgium and Luxembourg.[2] Her parents worked for the European Union. She attended the Sapienza University of Rome, where she studied physical organic chemistry.[2] She moved to the Mario Negri Institute for Pharmacological Research, where she worked toward a doctorate in cell biology with Daniela Corda. Her doctorate looked at the mechanisms that regulate the function of the carboxy-terminal binding protein 3/brefeldin A-ribosylated substrate (CtBP3/BARS) in the membrane fission of mammal cells and was awarded by the Open University.[3] Her PhD used high-contrast screening and mapping of genetics interactions.[2]
Research and career
After her PhD, Liberali then worked as a postdoctoral fellow in the Institute of Molecular Systems Biology at ETH Zurich.
In 2015, Liberali was made an assistant professor at the University of Basel. She was simultaneously appointed a group leader at the Friedrich Miescher Institute for Biomedical Research, where she was made Senior Group Leader in 2021.[4]
Liberali makes use of a systems biology approach to understand tissue organisation.[5] She is interested in the collective properties of multi-cellular systems and how their properties arise from the behaviour of individual cells.[6] With this information, Liberali looks to understand cell reprogramming and disease.[7] Her early work considered intestinal organoids[8] and how they develop from stem cells.[9][10]
In June 2022, Liberali was awarded the EMBO Gold Medal by the European Molecular Biology Organization.[11] She was awarded EMBO Membership in 2022.[12]
Awards and honours
- 2003 Italian Association for Cancer Research Fellowship[13]
- 2015 Swiss National Science Foundation Professorship[14][15]
- 2017 European Research Council (ERC) starting grant (SymBreakOragnoid)[16]
- 2019 EMBO Young Investigator[17][18]
- 2022 Friedrich Miescher Award[19]
- 2022 EMBO Gold Medal[20][21][22]
Selected publications
Personal life
Liberali is married with two children.[2] Her husband is Dutch and her children can speak five languages.[2] She has said that her guiding advice for someone about to start their own laboratory is "Sometimes good ideas need time, and the courage to just try them.".[2]
References
- Prisca Liberali publications from Europe PubMed Central
- "Cell scientist to watch – Prisca Liberali". Journal of Cell Science. 133 (10): jcs246272. 15 May 2020. doi:10.1242/jcs.246272. S2CID 219200956.
- Liberali, Prisca (2008). Mechanisms regulating the dual function of CtBP3/BARS in mammal cell membrane fission and transcription (PhD thesis). Open University. OCLC 500299520. EThOS 446099 ProQuest 301737291.
- FMI. "FMI - Friedrich Miescher Institute for Biomedical Research - Prisca Liberali". fmi.ch. Retrieved 2022-07-15.
- Prisca Liberali publications indexed by Google Scholar
- "Green light for 321 projects on self-chosen topics". Swiss National Science Foundation (SNSF) (in German). Retrieved 2022-07-15.
- FMI. "FMI - Friedrich Miescher Institute for Biomedical Research - Prisca Liberali". fmi.ch. Retrieved 2022-07-15.
- "Leaders of the Field Discuss Advances in Organoid Applications". stemcell.com. Retrieved 2022-07-15.
- "Don't be afraid, be bold - Interview with Prisca Liberali". Life Innovation Blog. 2021-02-11. Retrieved 2022-07-15.
- Lukonin, Ilya; Zinner, Marietta; Liberali, Prisca (October 2021). "Organoids in image-based phenotypic chemical screens". Experimental & Molecular Medicine. 53 (10): 1495–1502. doi:10.1038/s12276-021-00641-8. PMC 8569209. PMID 34663938.
- "Prisca is awarded the EMBO Gold Medal!". The Liberali Lab. 24 June 2022. Retrieved 2022-07-15.
- "EMBO elects 67 new members and associate members – Press releases – EMBO". 2022-07-06. Retrieved 2022-07-15.
- FMI. "FMI - Friedrich Miescher Institute for Biomedical Research - Prisca Liberali". fmi.ch. Retrieved 2022-07-15.
- "Liberali | Basel Stem Cell Network". baselstemcells.ch. Retrieved 2022-07-15.
- "Prof. Prisca Liberali - AcademiaNet". academia-net.org. Retrieved 2022-07-15.
- "ERC FUNDED PROJECTS".
- "Prisca becomes an EMBO Young Investigator". The Liberali Lab. 18 November 2019. Retrieved 2022-07-15.
- FMI. "Prisca Liberali becomes an EMBO Young Investigator". fmi.ch. Retrieved 2022-07-15.
- "Prisca Liberali awarded Friedrich Miescher Award". unibas.ch. Retrieved 2022-07-15.
- "Prisca Liberali awarded EMBO Gold Medal 2022 – Press releases – EMBO". 2022-06-24. Retrieved 2022-07-15.
- "Prisca Liberali awarded EMBO Gold Medal 2022". unibas.ch. Retrieved 2022-07-15.
- Seeing is believing: Meet Prisca Liberali, retrieved 2022-07-15
- Berend Snijder; Raphael Sacher; Pauli Rämö; Eva-Maria Damm; Prisca Liberali; Lucas Pelkmans (26 August 2009). "Population context determines cell-to-cell variability in endocytosis and virus infection". Nature. 461 (7263): 520–523. doi:10.1038/NATURE08282. ISSN 1476-4687. PMID 19710653. Wikidata Q39807636.
- Denise Serra; Urs Mayr; Andrea Boni; et al. (24 April 2019). "Self-organization and symmetry breaking in intestinal organoid development". Nature. 569 (7754): 66–72. doi:10.1038/S41586-019-1146-Y. ISSN 1476-4687. PMC 6544541. PMID 31019299. Wikidata Q90284285.
- Prisca Liberali; Elina Kakkonen; Gabriele Turacchio; et al. (20 March 2008). "The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS". The EMBO Journal. 27 (7): 970–981. doi:10.1038/EMBOJ.2008.59. ISSN 0261-4189. PMC 2323256. PMID 18354494. Wikidata Q30481720.