Prolycopene isomerase

Prolycopene isomerase (EC 5.2.1.13, CRTISO, carotene cis-trans isomerase, ZEBRA2 (gene), carotene isomerase, carotenoid isomerase) is an enzyme with systematic name 7,9,7',9'-tetracis-lycopene cis-trans-isomerase.[1][2][3][4] This enzyme catalyses the following chemical reaction

7,9,7',9'-tetracis-lycopene all-trans-lycopene
Prolycopene isomerase
Identifiers
EC no.5.2.1.13
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme is involved in carotenoid biosynthesis.

References

  1. Yu Q, Ghisla S, Hirschberg J, Mann V, Beyer P (March 2011). "Plant carotene cis-trans isomerase CRTISO: a new member of the FAD(RED)-dependent flavoproteins catalyzing non-redox reactions". The Journal of Biological Chemistry. 286 (10): 8666–76. doi:10.1074/jbc.m110.208017. PMC 3048748. PMID 21209101.
  2. Li Q, Farre G, Naqvi S, Breitenbach J, Sanahuja G, Bai C, Sandmann G, Capell T, Christou P, Zhu C (December 2010). "Cloning and functional characterization of the maize carotenoid isomerase and β-carotene hydroxylase genes and their regulation during endosperm maturation". Transgenic Research. 19 (6): 1053–68. doi:10.1007/s11248-010-9381-x. PMID 20221689. S2CID 1346977.
  3. Isaacson T, Ronen G, Zamir D, Hirschberg J (February 2002). "Cloning of tangerine from tomato reveals a carotenoid isomerase essential for the production of beta-carotene and xanthophylls in plants". The Plant Cell. 14 (2): 333–42. doi:10.1105/tpc.010303. PMC 152916. PMID 11884678.
  4. Chai C, Fang J, Liu Y, Tong H, Gong Y, Wang Y, Liu M, Wang Y, Qian Q, Cheng Z, Chu C (February 2011). "ZEBRA2, encoding a carotenoid isomerase, is involved in photoprotection in rice". Plant Molecular Biology. 75 (3): 211–21. doi:10.1007/s11103-010-9719-z. PMID 21161331. S2CID 286175.
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