Rectal discharge

Rectal discharge is intermittent or continuous expression of liquid from the anus (per rectum). Normal rectal mucus is needed for proper excretion of waste. Otherwise, this is closely related to types of fecal incontinence (e.g., fecal leakage) but the term rectal discharge does not necessarily imply degrees of incontinence. Types of fecal incontinence that produce a liquid leakage could be thought of as a type of rectal discharge.

Rectal discharge
Other namesAnal discharge, normal rectal mucus, anal drainage, anal seepage, anal leakage

Types

Different types of discharge are described. Generally "rectal discharge" refers to either a mucous or purulent discharge, but, depending upon what definition of rectal discharge is used, the following could be included:

Symptoms

There are many different types of rectal discharge, but the most common presentation of a discharge is passage of mucus or pus wrapped around an otherwise normal bowel movement.[10]

Rectal discharge has many causes, and may present with other symptoms:[10][11]

  • Staining of undergarments
  • Constant feeling of dampness around anus
  • Frequent urge to open bowels, but passage of only small amounts of mucus or pus-like liquid rather than normal feces
  • Rectal pain
  • Rectal malodor, when the discharge is foul-smelling, e.g. associated with certain infections
  • Pruritus ani
  • Rectal bleeding
  • Perianal erythema, swelling and tenderness

Purulent rectal discharge (suppurative discharge)

Pus usually indicates infection. Frequently medical sources do not differentiate between the two types of discharge, instead using the general term mucopurulent discharge, which, strictly speaking, should only be used to refer to a discharge that contains both mucus and pus. Purulent discharges may be blood-streaked.

Mucous rectal discharge (mucinous rectal discharge, mucoid rectal discharge)

Mucus coats the walls of the colon in health, functioning as a protective barrier and also to aid peristalsis by lubrication of stool. Mucous discharges can be thought of in three broad categories:

  • Normal physiologically produced mucus
  • Inappropriately expressed physiologically produced mucus (e.g. in the presence of sphincter defects, or lesions preventing normal sphincter closure, allowing seepage or soiling)
  • Mucus produced in pathological quantities (e.g. from a lesion, or generalized coloproctitis or as a result of bacterial overgrowth)

A mucous rectal discharge may be blood-streaked. With some conditions, the blood can be homogenously mixed with the mucus, creating a pink goo. An example of this could be the so-called "red currant jelly" stools in intussusception. This appearance refers to the mixture of sloughed mucosa, mucus, and blood.[12]

Note: "mucus" is a noun, used to name the substance itself, and "mucous" is an adjective, used to describe a discharge. "Mucoid" is also an adjective and means mucus-like. "Mucinous" strictly speaking refers to something having a mucin-like attribute, but it often is used interchangeably with the word "mucous" (as mucus usually contains a high percentage of mucin).

Differential diagnosis

The differential diagnosis of rectal discharge is extensive, but the general etiological themes are infection and inflammation.[11] Some lesions can cause a discharge by mechanically interfering with, or preventing the complete closure of, the anal canal. This type of lesion may not cause discharge intrinsically, but instead, allow transit of liquid stool components and mucus.

Perianal Crohn's disease is associated with fistulizing, fissuring and perianal abscess formation.[18]

After colostomy, the distal section of bowel continues to produce mucus despite fecal diversion, often resulting in mucinous discharge.[19]

Occasionally, intestinal parasitic infection can present with discharge, for example whipworm.[20]

Perianal discharge
Two (2) pilonidal cysts in the intergluteal cleft showing mucopurulent discharge.

Several pathologies can present with perianal discharge. Although not exactly the same as rectal discharge, perianal discharge can be misinterpreted as such, given the anatomical proximity.

Fistulae draining into the perianal region, as well as pilonidal diseases, are the main entities that fall within this category. Perianal tumours can also discharge when they fungate or otherwise become cystic or necrotic.

Causes

Proctitis
Main article: Proctitis

Proctitis is inflammation of the lining of the rectum[21] including the distal 15 cm (6 in) of the rectum.

Proctitis has many causes. Common infection causes include: sexual intercourse with someone who has a sexually transmitted disease (STD), infection from a foodborne illness, and strep throat (in children).[22] Proctitis may also be caused by some types of inflammatory bowel disease, radiation therapy, injury to the rectum or anus, or some types of antibiotic.[22]

Tuberculosis proctitis can create a mucous discharge.[23]

Anal warts (condyloma acuminatum, anogenital warts)
Main article: Anogenital warts

Anal warts are irregular, verrucous lesions caused by human papilloma virus. Anal warts are usually transmitted by unprotected, anoreceptive intercourse. Anal warts may be asymptomatic,[24] or may cause rectal discharge, anal wetness, rectal bleeding, and pruritus ani.[14] Lesions can also occur within the anal canal, where they are more likely to create symptoms.

Chlamydia
Main article: Lymphogranuloma venereum

The bacterium Chlamydia trachomatis can cause 2 conditions in humans; viz. trachoma and lymphogranuloma venereum. Trachoma can cause an asymptomatic proctitis, but the symptoms of lymphogranuloma venereum are usually more severe, including pruritus ani, purulent rectal discharge, hematochezia rectal pain and diarrhea or constipation.[14][24] Lymphogranuloma venereum can cause fistulas, strictures and anorectal abscesses if left untreated. Hence, it can be confused with Crohn's disease.[25][26]

Rectal gonorrhea
Main article: Gonorrhea

Rectal gonorrhea is caused by Neisseria gonorrhoeae.[24] The condition is usually asymptomatic, but symptoms can include rectal discharge (which can be creamy, purulent or bloody), pruritus ani, tenesmus, and possibly constipation. When symptomatic, these usually appear 5–7 days post-exposure.[14] Discharge is the most common symptom, and it is usually a brownish mucopurulent consistency.[27]

Syphilis
Main article: Syphilis

Anorectal syphilis is caused by Treponema pallidum and is contracted through anoreceptive intercourse. Symptoms are usually minimal, but mucous discharge, bleeding, and tenesmus may be present.[27]

Ulcerative colitis
Main article: Ulcerative colitis

Diversion colitis
Main article: Diversion colitis

When the fecal stream is diverted as part of a colostomy, a condition called diversion colitis may develop in the section of bowel that no longer is in contact with stool. The mucosal lining is nourished by short-chain fatty acids, which are produced as a result of bacterial fermentation in the gut. Long-term lack of exposure to these nutrients can cause inflammation of the colon (colitis).[28] Symptoms include rectal bleeding, mucous discharge, tenesmus, and abdominal pain.[27]

Volvulus
Main article: Volvulus

Colonic ulcers
Main article: Colonic ulcer

Mucosal prolapse syndromes

Irritable bowel syndrome
Main article: Irritable bowel syndrome

Pneumatosis cystoides intestinalis
Main article: Pneumatosis cystoides intestinalis

Pruritus ani
Main article: Pruritus ani

Anal carcinoma
Main article: Anal cancer

Anal carcinoma is much less common than colorectal cancer. The most common form is squamous cell carcinoma, followed by adenocarcinoma and melanoma.[29] SCC usually occurs in the anal canal, and more rarely on the anal margin. Anal margin SCC presents as a lesion with rolled, everted edges and central ulceration.[27] Symptoms include a painful lump, bleeding, pruritus ani, tenesmus, discharge or possibly fecal incontinence. SSC in the anal canal most commonly causes bleeding, but may also cause anal pain, a lump, pruritus ani, discharge, tenesmus, change in bowel habits and fecal incontinence. Because these symptoms are so unspecific, and because symptoms of anal carcinoma may not always be typical, this can lead to delays in diagnosis.[30]

Rare neoplasms at this site that can give rise to discharge include Paget's disease (which is possibly a type of adenocarcinoma) and verrucous carcinoma.[27]

Colorectal cancer
Main article: Colorectal cancer

Pelvic sepsis
Main article: Pelvic sepsis

Orlistat
Main article: Orlistat

Colorectal polyp
Main article: Polyp (medicine)

Adenoma is the most common colorectal polyp. Adenomas are not malignant, but rarely adenocarcinoma can develop from them. Large adenomas can cause rectal bleeding, mucus discharge, tenesmus, and a sensation of urgency. Mucus production may be so great that it can cause electrolyte disturbances in the blood.[27]

Juvenile polyps

Juvenile polyps may cause rectal discharge.

Familial adenomatous polyposis
Main article: Familial adenomatous polyposis

See also

References
  1. Adam S Cheifetz; Alphonso Brown; Michael Curry; Alan C Moss (10 Mar 2011). Oxford American Handbook of Gastroenterology and Hepatology. Oxford University Press. p. 234. ISBN 9780199830121.
  2. Robles, I; Vásquez, JM; Loehnert, R; Espino, A; Biel, F; Correa, I; Gobelet, J; Sáenz, M; Saenz, C; Sáenz, R (February 2012). "[Orange oily anal leakage: a new entity linked to dietary changes]". Gastroenterologia y Hepatologia. 35 (2): 74–7. doi:10.1016/j.gastrohep.2011.11.009. PMID 22266298.
  3. Ling, KH; Nichols, PD; But, PP (2009). "Fish-induced keriorrhea". Advances in Food and Nutrition Research. 57: 1–52. doi:10.1016/S1043-4526(09)57001-5. PMID 19595384.
  4. Berman, P; Harley, EH; Spark, AA (May 23, 1981). "Keriorrhoea--the passage of oil per rectum--after ingestion of marine wax esters". South African Medical Journal. 59 (22): 791–2. PMID 7195080.
  5. Vernava AM, Moore BA, Longo WE, Johnson FE (1997). "Lower gastrointestinal bleeding". Dis. Colon Rectum. 40 (7): 846–58. doi:10.1007/BF02055445. PMID 9221865. S2CID 6971032.
  6. MedlinePlus Encyclopedia: Bloody or tarry stools, retrieved 19 July 2010.
  7. Taber's Cyclopedic Medical Dictionary. Donald Venes. 20th Edition. Page 955.
  8. "Diarrhea". The Lecturio Medical Concept Library. Retrieved 3 October 2021.
  9. "Diarrhoeal disease Factsheet". World Health Organization. 2 May 2017. Retrieved 29 October 2020.
  10. "Rectal discharge". Queensland health. Archived from the original on 20 April 2012. Retrieved 10 July 2012.
  11. Schueler, Stephen. "Anal Discharge: Overview". Retrieved 18 July 2012.
  12. Yamamoto, LG; Morita, SY; Boychuk, RB; Inaba, AS; Rosen, LM; Yee, LL; Young, LL (May 1997). "Stool appearance in intussusception: assessing the value of the term "currant jelly"". The American Journal of Emergency Medicine. 15 (3): 293–8. doi:10.1016/s0735-6757(97)90019-x. PMID 9148991.
  13. Gupta, PJ (July 2005). "A study of suppurative pathologies associated with chronic anal fissures". Techniques in Coloproctology. 9 (2): 104–7. doi:10.1007/s10151-005-0206-5. PMID 16007366. S2CID 8125271.
  14. al., edited by Tadataka Yamada; associate editors, David H. Alpers ... et (2009). Textbook of gastroenterology (5th ed.). Chichester, West Sussex: Blackwell Pub. ISBN 978-1-4051-6911-0. {{cite book}}: |first= has generic name (help)CS1 maint: multiple names: authors list (link)
  15. McCutcheon, T (Sep–Oct 2009). "Anal condyloma acuminatum". Gastroenterology Nursing. 32 (5): 342–9. doi:10.1097/SGA.0b013e3181b85d4e. PMID 19820442. S2CID 26111540.
  16. Knott, Laurence. "Gonorrhoea". Patient.info.
  17. Urrejola, G; Villalón, R; Rodríguez, N (February 2010). "[Perianal tuberculosis: report of two cases]". Revista Médica de Chile. 138 (2): 220–2. doi:10.4067/s0034-98872010000200012. PMID 20461312.
  18. Solomon, MJ (1996). "Fistulae and abscesses in symptomatic perianal Crohn's disease". International Journal of Colorectal Disease. 11 (5): 222–6. doi:10.1007/s003840050051. PMID 8951512. S2CID 20489800.
  19. "About rectal discharge" (PDF). Colostomy association.
  20. Feigen, GM (August 1987). "Suppurative anal cryptitis associated with Trichuris trichiura. Report of a case". Diseases of the Colon and Rectum. 30 (8): 620–2. doi:10.1007/bf02554810. PMID 3622166. S2CID 189776901.
  21. "Definition & Facts for Proctitis | NIDDK". National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved 2019-05-06.
  22. "Symptoms & Causes of Proctitis | NIDDK". National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved 2019-05-06.
  23. Gierthmühlen, M; Laiffer, G; Viehl, CT; Savic, S; Bremerich, J; Mueller, C; Christ, M (April 2008). "[No ordinary anal fistula...]". Der Internist. 49 (4): 490, 492–4. doi:10.1007/s00108-008-2063-6. PMID 18320154.
  24. Warren, RE (August 1987). "Ano-rectal symptoms of sexually transmitted disease". Canadian Family Physician. 33: 1859–62. PMC 2218235. PMID 21263807.
  25. "Crohn's Disease". The Lecturio Medical Concept Library. 28 August 2020. Retrieved 3 October 2021.
  26. "Crohn's disease". NHS UK. 23 October 2017. Retrieved 3 October 2021.
  27. al., senior editors, Bruce G. Wolff ... et (2007). The ASCRS textbook of colon and rectal surgery. New York: Springer. ISBN 978-0-387-24846-2. {{cite book}}: |first= has generic name (help)CS1 maint: multiple names: authors list (link)
  28. Roediger, WE (October 1990). "The starved colon—diminished mucosal nutrition, diminished absorption, and colitis". Diseases of the Colon and Rectum. 33 (10): 858–62. doi:10.1007/bf02051922. PMID 2209275. S2CID 30766753.
  29. Klas, JV; Rothenberger, DA; Wong, WD; Madoff, RD (Apr 15, 1999). "Malignant tumors of the anal canal: the spectrum of disease, treatment, and outcomes". Cancer. 85 (8): 1686–93. doi:10.1002/(sici)1097-0142(19990415)85:8<1686::aid-cncr7>3.0.co;2-7. PMID 10223561.
  30. Jensen, SL; Hagen, K; Shokouh-Amiri, MH; Nielsen, OV (May 1987). "Does an erroneous diagnosis of squamous-cell carcinoma of the anal canal and anal margin at first physician visit influence prognosis?". Diseases of the Colon and Rectum. 30 (5): 345–51. doi:10.1007/bf02555452. PMID 3568924. S2CID 45620187.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.