Soumya Raychaudhuri

Soumya Raychaudhuri is a Professor of Medicine and Biomedical Informatics at Harvard Medical School, and an Institute Member at Broad Institute.[1] He is the JS Coblyn and MB Brenner Distinguished Chair in Rheumatology/Immunology and a practicing rheumatologist at Brigham and Women's Hospital. He is the Director for the Center for Data Sciences at Brigham and Harvard. In addition, he serves as a Visiting Professor in Genetics at the University of Manchester. His research focuses on human genetics and computational genomics to understand immune-mediated diseases.[2][3]

Soumya Raychaudhuri
Born (1975-10-10) October 10, 1975
Alma mater
Scientific career
FieldsComputational biology genetics immunology
Institutions
Doctoral advisor
Websiteimmunogenomics.hms.harvard.edu/people/soumya-raychaudhuri

Education and career

Raychaudhuri completed his undergraduate degrees in biophysics and mathematics from State University of New York at Buffalo in 1997.[4] He went on to join the Stanford University Medical School where he completed his M.D. and Ph.D. degrees. He pursued clinical training in internal medicine, followed by subspecialty training in rheumatology at BWH. He concurrently completed postdoctoral training in human genetics at the Broad Institute with Mark Daly. In 2010, he launched his laboratory and joined the faculty at Harvard Medical School. He was promoted to Professor in 2018.

His lab[5] at Harvard uses human genetics,[6] functional genomics and bioinformatics techniques to study immune mediated diseases, such as rheumatoid arthritis[7][8] and tuberculosis.[9][10] His lab has also been active in investigating the genetic basis of other diseases including age related macular degeneration[11] and type I diabetes.[12]

Awards & memberships
  • Doris Duke Award[13]
  • American College of Rheumatology Henry Kunkel Young Investigator Award[14]
  • Elected member of American Society of Clinical Investigation[15]

References
  1. "Soumya Raychaudhuri". www.broadinstitute.org. January 23, 2019. Retrieved November 3, 2020.
  2. "Soumya Raychaudhuri". dbmi.hms.harvard.edu. Retrieved October 28, 2020.
  3. "Soumya Raychaudhuri". scholar.google.com. Retrieved October 28, 2020.
  4. "May 15, 1997-Commencement Extra: Awards to honor students for leadership, academic excellence". www.buffalo.edu. Retrieved November 7, 2020.
  5. "The Raychaudhuri Lab". immunogenomics.hms.harvard.edu. Retrieved October 28, 2020.
  6. Asgari, S; Luo, Y; Akbari, A; Belbin, GM; Li, X; Harris, DN; Selig, M; Bartell, E; Calderon, R; Slowikowski, K; Contreras, C; Yataco, R; Galea, JT; Jimenez, J; Coit, JM; Farroñay, C; Nazarian, RM; O'Connor, TD; Dietz, HC; Hirschhorn, JN; Guio, H; Lecca, L; Kenny, EE; Freeman, EE; Murray, MB; Raychaudhuri, S (June 2020). "A positively selected FBN1 missense variant reduces height in Peruvian individuals". Nature. 582 (7811): 234–239. Bibcode:2020Natur.582..234A. doi:10.1038/s41586-020-2302-0. PMC 7410362. PMID 32499652.
  7. Raychaudhuri, S; Sandor, C; Stahl, EA; Freudenberg, J; Lee, HS; Jia, X; Alfredsson, L; Padyukov, L; Klareskog, L; Worthington, J; Siminovitch, KA; Bae, SC; Plenge, RM; Gregersen, PK; de Bakker, PI (January 29, 2012). "Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis". Nature Genetics. 44 (3): 291–6. doi:10.1038/ng.1076. PMC 3288335. PMID 22286218.
  8. Zhang, F; Wei, K; Slowikowski, K; Fonseka, CY; Rao, DA; Kelly, S; Goodman, SM; Tabechian, D; Hughes, LB; Salomon-Escoto, K; Watts, GFM; Jonsson, AH; Rangel-Moreno, J; Meednu, N; Rozo, C; Apruzzese, W; Eisenhaure, TM; Lieb, DJ; Boyle, DL; Mandelin AM, 2nd; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE), Consortium.; Boyce, BF; DiCarlo, E; Gravallese, EM; Gregersen, PK; Moreland, L; Firestein, GS; Hacohen, N; Nusbaum, C; Lederer, JA; Perlman, H; Pitzalis, C; Filer, A; Holers, VM; Bykerk, VP; Donlin, LT; Anolik, JH; Brenner, MB; Raychaudhuri, S (July 2019). "Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry". Nature Immunology. 20 (7): 928–942. doi:10.1038/s41590-019-0378-1. PMC 6602051. PMID 31061532.
  9. Nathan, A; Beynor, JI; Baglaenko, Y; Suliman, S; Ishigaki, K; Asgari, S; Huang, CC; Luo, Y; Zhang, Z; Lopez, K; Lindestam Arlehamn, CS; Ernst, JD; Jimenez, J; Calderón, RI; Lecca, L; Van Rhijn, I; Moody, DB; Murray, MB; Raychaudhuri, S (June 2021). "Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease". Nature Immunology. 22 (6): 781–793. doi:10.1038/s41590-021-00933-1. PMC 8162307. PMID 34031617.
  10. Luo, Y; Suliman, S; Asgari, S; Amariuta, T; Baglaenko, Y; Martínez-Bonet, M; Ishigaki, K; Gutierrez-Arcelus, M; Calderon, R; Lecca, L; León, SR; Jimenez, J; Yataco, R; Contreras, C; Galea, JT; Becerra, M; Nejentsev, S; Nigrovic, PA; Moody, DB; Murray, MB; Raychaudhuri, S (August 21, 2019). "Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians". Nature Communications. 10 (1): 3765. Bibcode:2019NatCo..10.3765L. doi:10.1038/s41467-019-11664-1. PMC 6704092. PMID 31434886.
  11. Seddon, JM; Yu, Y; Miller, EC; Reynolds, R; Tan, PL; Gowrisankar, S; Goldstein, JI; Triebwasser, M; Anderson, HE; Zerbib, J; Kavanagh, D; Souied, E; Katsanis, N; Daly, MJ; Atkinson, JP; Raychaudhuri, S (November 2013). "Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration". Nature Genetics. 45 (11): 1366–70. doi:10.1038/ng.2741. PMC 3902040. PMID 24036952.
  12. Hu, X; Deutsch, AJ; Lenz, TL; Onengut-Gumuscu, S; Han, B; Chen, WM; Howson, JM; Todd, JA; de Bakker, PI; Rich, SS; Raychaudhuri, S (August 2015). "Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk". Nature Genetics. 47 (8): 898–905. doi:10.1038/ng.3353. PMC 4930791. PMID 26168013.
  13. "Doris Duke Charitable Foundation Awards $7.8 Million to Sixteen Physician-Scientists". Candid. July 19, 2013. Archived from the original on July 16, 2015.
  14. "The 2016 ACR Award Winners Discuss Their Contributions to Rheumatology Research, Education, Patient Care - Page 5 of 11". The Rheumatologist. Retrieved October 28, 2020.
  15. "The American Society for Clinical Investigation". Retrieved October 28, 2020.
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