Russ Altman

Russ Biagio Altman is an American professor of bioengineering, genetics, medicine, and biomedical data science (and of computer science, by courtesy) and past chairman of the bioengineering department at Stanford University.

Russ Biagio Altman
Russ B. Altman in 2007
Born
Brooklyn, New York[1]
Alma materHarvard College
Stanford University
Scientific career
InstitutionsStanford University
ThesisExclusion methods for the determination of protein structure from experimental data[2] (1989)
External video
video icon What really happens when you mix medications?, 14:41, TED talks[3]

Education

Altman holds an A.B. from Harvard College in 1983, a Ph.D. in medical information sciences from Stanford in 1989 and M.D. from Stanford Medical School in 1990.[2] After his internship at Stanford, he became board certified in 1991 in internal medicine and in clinical informatics in 2014. After a year of post-doctoral research, he joined the faculty as assistant professor in 1992. He became full professor in 2004, and was chair of the department of bioengineering from 2007 to June 2012.[1] He currently is the Kenneth Fong Professor of Engineering at Stanford, and an advisor to the Chan Zuckerberg Biohub. As of 2018, Altman was a founding co-editor of the Annual Review of Biomedical Data Science.[4]

Research and career

His primary research interests are in the application of computing and informatics technologies to problems relevant to medicine. He is particularly interested in methods for understanding drug action at molecular, cellular, organism and population levels. His lab studies how human genetic variation impacts drug response, helping start the PharmGKB project in 2000.[5] Other work focuses on the analysis of biological molecules to understand the actions, interactions and adverse events of drugs, publishing a database called FEATURE in 2003.[6][7] He helps lead an FDA-supported center for regulatory science and innovation (CERSI).[8] He chaired the Science Board advising the FDA Commissioner, serves on the NIH director’s advisory committee, and is co-chair of the IOM Drug Forum. He is an organizer of the annual Pacific Symposium on Biocomputing. He co-founded Personalis, Inc. in 2011 along with three other faculty members including Euan Ashley, Atul Butte, Michael Snyder and businessman John West.[9] In 2017, he started hosting a show on SiriusXM (Insight Channel 121) titled "The Future of Everything".[10] He is clinically active with a pharmacogenomics consultative service at Stanford Healthcare.

Awards and honors

Altman received the U.S. Presidential Early Career Award for Scientists and Engineers (1997) and a National Science Foundation CAREER Award (1996). He is a fellow of the American College of Physicians (ACP), the American College of Medical Informatics (ACMI), the American Institute for Medical and Biological Engineering (AIMBE), and the American Association for the Advancement of Science (AAAS). He is a member of the National Academy of Medicine (formerly the Institute of Medicine) of the National Academies. He was president (2000 to 2002), founding board member, and a Fellow of the International Society for Computational Biology (ISCB), and-president of the American Society for Clinical Pharmacology & Therapeutics (ASCPT) from March 2013 to 2014.[11]

He received the Stanford Medical School graduate teaching award in 2000, and mentorship award in 2014.

In 2018, Altman was awarded the ISCB Outstanding Contributions Award.[12]

References
  1. "Curriculum Vitae: Russ Biagio Altman, MD, PhD". CAP profile. Stanford School of Medicine. March 2015. Retrieved April 1, 2017.
  2. Russ B. Altman (1989). Exclusion methods for the determination of protein structure from experimental data (phd). Stanford University.
  3. "What really happens when you mix medications?". TED (talks). 2 March 2016. Retrieved April 2, 2016.
  4. Altman, Russ B.; Levitt, Michael (2018). "What is Biomedical Data Science and do We Need an Annual Review of It?". Annual Review of Biomedical Data Science. 1: i–iii. doi:10.1146/annurev-bd-01-041718-100001.
  5. Klein TE, Chang JT, Cho MK, Easton KL, Fergerson R, Hewett M, Lin Z, Liu Y, Liu S, Oliver DE, Rubin DL, Shafa F, Stuart JM, Altman RB (2001). "Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base". The Pharmacogenomics Journal. 1 (3): 167–170. doi:10.1038/sj.tpj.6500035. PMID 11908751.
  6. Liang MP, Banatao DR, Klein TE, Brutlag DL, Altman RB (July 1, 2003). "WebFEATURE: an interactive web tool for identifying and visualizing functional sites on macromolecular structures". Nucleic Acids Research. 31 (13): 3324–7. doi:10.1093/nar/gkg553. PMC 168960. PMID 12824318.
  7. "Citations and publications". WebFEATURE web site. Retrieved April 1, 2017.
  8. "Home | UCSF-Stanford Center of Excellence in Regulatory Science and Innovation (CERSI) | UCSF".
  9. "About Us: Pioneering Genome-Guided Medicine". Personalis web site. Retrieved April 1, 2017.
  10. "Stanford Radio". Retrieved April 1, 2017.
  11. "ASCPT News". Clinical Pharmacology & Therapeutics. 93 (3): 222–227. December 18, 2012. doi:10.1038/clpt.2012.248. S2CID 221604509.
  12. "February 14, 2018: ISCB Congratulates the 2018 ISCB Award Winners!". www.iscb.org. Retrieved 15 February 2018.
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