Sudhanshu Vrati

Sudhanshu Vrati (born 19 March 1960) is an Indian immunologist, microbiologist and the director of the Regional Centre for Biotechnology. Known for his studies in the fields of RNA virus replication and vaccine development, Vrati is an elected fellow of the National Academy of Sciences, India, Indian National Science Academy and the Indian Academy of Sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2003.[1]

Sudhanshu Vrati
Born (1960-03-19) 19 March 1960
Uttar Pradesh, India
NationalityIndian
Alma mater
Known forStudies in RNA virus replication and vaccine development
Awards
Scientific career
Fields
Institutions

Biography
G. B. Pant University of Agriculture and Technology - Office of the vice chancellor
Making of a DNA vaccine

Born on 19 March 1960 in the Indian state of Uttar Pradesh,[2] Sudhanshu Vrati earned an MSc in microbiology from G. B. Pant University of Agriculture and Technology and did a DIIT in biochemical engineering at the Indian Institute of Technology, Delhi.[3] Subsequently, he moved to Australia for his doctoral studies and secured a PhD in biochemistry from the Australian National University. His post-doctoral work was at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) center in Sydney and on his return to India, he joined the National Institute of Immunology as a scientist.[4] He was working as a senior scientist when he was appointed as the dean at the Translational Health Science and Technology Institute (THSTI) in 2005.[5] In October 2015, he was transferred, on deputation, to the Regional Centre for Biotechnology (RCB) as its executive director, a position he holds to date.[3] He is also a visiting scientist at the Pasteur Institute, Paris and an executive director of Bharat Immunologicals and Biologicals Corporation,[6] a Government of India undertaking involved in the manufacture of vaccines and immunizers.[7]

Legacy

Vrati's early researches at THSTI focused on JEV life-cycle like receptor binding and entry mechanisms, molecular mechanisms of virus replication, assembly, egress as well as the clinical development of an oral rotavirus vaccine. Later, he concentrated on the development of DNA vaccines and the details of the work has since been published as an article, DNA vaccines: Getting closer to becoming a reality, in 2013.[8] His work on rat brains help identify Mov34 protein which has assisted in the development of vaccines for flaviviral diseases like Japanese encephalitis and Dengue.[9] His studies have been documented by way of a number of articles.[10][11][note 1] Besides, he has contributed chapters to books edited by others.[12][13] He holds several patents for the process he has developed.[14][15][16]

Awards and honors

It was during his days at the National Institute of Immunology, Vrati received the 2001 VASVIK Industrial Research Award.[17] The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2003;[1] the elected membership of the Guha Research Conference reached him the same year.[3] He was elected as a fellow by the National Academy of Sciences, India in 2004;[18] the same year as he received the elected fellowship of the Indian Academy of Sciences.[19] The Indian National Science Academy selected him for the Professor KP Bhargava Memorial Medal[20] and the Association of Microbiologists of India chose him for the Alembic Award, both in 2005.[21] The National Academy of Sciences, India honored him again in 2006 with the NASI-Reliance Platinum Jubilee Award.[22] He received the Tata Innovation Fellowship of the Department of Biotechnology in 2009 and the High Commission of Australia in India awarded him the Australian Alumni Award in 2010[23] The award orations delivered by him include the 2003 edition of the Dr. J. B. Srivastava Oration of the Indian Council of Medical Research.[24] In 2021, he was conferred the prestigious J C Bose National Fellowship of SERB.

Selected bibliography

Chapters
  • Malik Zainul Abdin, Usha Kiran, Kamaluddin, Athar Ali (Eds.); Mohan Babu Appiahgari, Usha Kiran, Athar Ali, Sudhanshu Vrati, Malik Zainul Abdeen (Chapter authors) (10 March 2017). "Plant-based Edible Vaccines: Issues and Advantages". Plant Biotechnology: Principles and Applications. Springer. pp. 329–. ISBN 978-981-10-2961-5.{{cite book}}: CS1 maint: multiple names: authors list (link)

Articles

See also

Notes
  1. Please see Selected bibliography section

References
  1. "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Archived from the original (PDF) on 4 March 2018. Retrieved 20 November 2017.
  2. "Fellow profile". Indian Academy of Sciences. 12 November 2017. Retrieved 12 November 2017.
  3. "Vrati on THSTI" (PDF). Translational Health Science and Technology Institute. 12 December 2017. Retrieved 12 December 2017.
  4. "Director profile". Regional Centre for Biotechnology. 12 December 2017. Retrieved 12 December 2017.
  5. Desk, BioVoice News (15 October 2016). "Prof Sudhanshu Vrati takes charge as Executive Director at RCB, Faridabad". BioVoiceNews. Retrieved 12 December 2017.
  6. 4-traders. "Sudhanshu Vrati, PhD - Biography". www.4-traders.com. Retrieved 12 December 2017.
  7. "About BIBCOL – National Institute of Solar Energy". www.bibcol.com. 12 December 2017. Retrieved 12 December 2017.
  8. Kaushik Bharati, Sudhanshu Vrati (2013). "DNA vaccines: Getting closer to becoming a reality". Indian J Med Res. 137 (6): 1027–8. PMC 3734707. PMID 23852283.
  9. Gregory R. Bock; Jamie A. Goode (2 October 2006). New Treatment Strategies for Dengue and Other Flaviviral Diseases. John Wiley & Sons. pp. 147–. ISBN 978-0-470-05801-5.
  10. "Browse by Fellow". Indian Academy of Sciences. 6 December 2017. Retrieved 6 December 2017.
  11. "On Google Scholar". Google Scholar. 23 November 2017. Retrieved 23 November 2017.
  12. Malik Zainul Abdin; Usha Kiran; Kamaluddin, Athar Ali (10 March 2017). Plant Biotechnology: Principles and Applications. Springer. pp. 329–. ISBN 978-981-10-2961-5.
  13. Ta, M.; Vrati, S. (June 2000). "Mov34 protein from mouse brain interacts with the 3' noncoding region of Japanese encephalitis virus". Journal of Virology. 74 (11): 5108–5115. doi:10.1128/jvi.74.11.5108-5115.2000. ISSN 0022-538X. PMC 110863. PMID 10799585.
  14. "Sudhanshu VRATI Inventions, Patents and Patent Applications". patents.justia.com. 12 December 2017. Retrieved 12 December 2017.
  15. "Novel japanese encephalitis vaccine and method of manufacturing the same". Google Patents. 12 December 2017. Retrieved 12 December 2017.
  16. "Dna encoding ovine adenovirus (oav287) and its use as a viral vector". Google Patents. 12 December 2017. Retrieved 12 December 2017.
  17. "Biological Sciences & Technology". www.vasvik.org. 12 December 2017. Archived from the original on 14 June 2021. Retrieved 12 December 2017.
  18. "NASI Year Book 2015" (PDF). National Academy of Sciences, India. 24 November 2017. Archived from the original (PDF) on 6 August 2015. Retrieved 24 November 2017.
  19. "Fellowship - Indian Academy of Sciences". www.ias.ac.in. 12 December 2017. Retrieved 12 December 2017.
  20. "Professor KP Bhargava Memorial Medal". Indian National Science Academy. 12 December 2017. Retrieved 12 December 2017.
  21. "Alembic Award". Association of Microbiologists of India. 12 December 2017. Retrieved 12 December 2017.
  22. "NASI-Reliance Industries Platinum Jubilee Award". National Academy of Sciences, India. 12 December 2017. Retrieved 12 December 2017.
  23. "Australian Alumni Award" (PDF). National Institute of Immunology. 12 December 2017. Retrieved 12 December 2017.
  24. "ICMR Awards and Prizes" (PDF). Indian Council of Medical Research. 12 December 2017. Archived from the original (PDF) on 4 March 2016. Retrieved 12 December 2017.

Further reading
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