Tagatose kinase
In enzymology, a tagatose kinase (EC 2.7.1.101) is an enzyme that catalyzes the chemical reaction
- ATP + D-tagatose ADP + D-tagatose 6-phosphate
tagatose kinase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 2.7.1.101 | ||||||||
CAS no. | 39434-00-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
Thus, the two substrates of this enzyme are ATP and D-tagatose, whereas its two products are ADP and D-tagatose 6-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-tagatose 6-phosphotransferase. Other names in common use include tagatose 6-phosphate kinase (phosphorylating), D-tagatose 6-phosphate kinase, and tagatose-6-phosphate kinase. This enzyme participates in galactose metabolism.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2FIQ.
References
- Szumiøo T (August 1981). "A novel enzyme, tagatose kinase, from Mycobacterium butyricum". Biochimica et Biophysica Acta (BBA) - Enzymology. 660 (2): 366–70. doi:10.1016/0005-2744(81)90182-0. PMID 6269638.