Tum Hi Ho Bandhu Sakha Tumhi

The story revolves around the Pethewala family. Bhushan, the second son of the family is in love with Shreya. Before he can tell his family, they pretend to have fixed his marriage elsewhere but the girl turns out to be Shreya. The lovers are happily married.

Ajay is the youngest son of the Pethewala family. His best friend Ajju is in love with Sanjana. Ajju gets a job in USA and he and Sanjana decide to marry in the court given Sanjana's father's objections. Being just under 21 years of age, Ajju cannot marry. To stop Sanjana's father from getting her married forcibly to someone else, Ajju requests Ajay to marry her till he returns from the US.

Ajay marries Sanjana. Unknown to their families is that their marriage is a contract for a few months. The Pethewala family takes time to accept Sanjana. Meanwhile, Shreya, after getting brain washed by her mother, wants to divide the house and gain control over it. Sanjana discovers Shreya's true colours and tries to expose her. But Shreya exposes the truth behind Ajay's marriage. This creates huge problems in the family and Sanjana is thrown out of the house. Trilokchand asks Ajay to go for a divorce. But Sanjana's father, who has already accepted the marriage makes her realise her love for Ajay. Ajay likes Sanjana but hides his feelings as he does not want to hurt Ajju. Sanjana tries to win Ajay's love. Meanwhile, Dadi realises Shreya's true face. She brings back Sanjana to the house as a negative person. Sanjana tortures the family so the torn apart family will cooperate to fight her. She finally exposes Shreya who is thrown out by Bhushan.

Shreya tries to commit suicide by jumping off from the cliff. Bhushan saves her but she loses her vision and becomes blind. Shreya regrets her mistakes and asks forgiveness from the family. Everyone forgives her except Bhushan. At the same time Ajju returns from USA. Ajju learns of Sanjana's love for Ajay. He tries to drag her out of the house but Ajay stops him and confesses his love for her. This creates a huge fight between the friends. Ajju tries to rape Sanjana, when Ajay's sister Mishri saves her by hitting Ajju on his head with a vase. Ajju dies and Mishri gets scared. Ajay and Sanjana hide Ajju's body. The cops come by and tell Trilokchand that they've discovered Ajju's body and that the entire Pethewala family are suspects in the murder, but Ajay and Sanjana are the main suspects. In college, Mishri notices that she is being followed. It is actually Ajju in disguise. Ajju's sister Shaina, Ajju and even Shreya try and manipulate Mishri into thinking she's going mad but Ajay and Sanjana protect her. In the meantime, Shreya has faked a pregnancy to stay in the family but Bhushan suspects her and discovers her lies. Ajay and Mishri catch another man, Anuj, who claims to have fallen in love with Mishri at first sight. Anuj's family asks for Mishri's hand in marriage. On the day of the wedding, Sanjana is arrested for Ajju's murder. Sanjana confesses and the only way Ajay can save her is to marry Shaina. Finally Bhushan enters and exposes all the villains and made Sanjana and Ajay married. Shreya, Ajay and shaina are arrested. Sanjana requests Bhushan to bring Shreya home but he agrees. Shreya gets happy that Sanjana forgives her. The story ends with the whole family dancing.

• Chandni Bhagwanani as Sanjana Ajay Pethewala=Wife of Ajay Petewala.Chachi of Samar.
• Kabeer Kumar as Ajay Pethewala=Trilokchand and Elaichi's Fourth son=youngest brother of Amar,Bhushan,and Aayush.elder brother of Utpal,Avni,and Mishri.Chachu of Samar.Husband of Sanjana.
• Neil Bhatt as Bhushan Trilokchand Pethewala=Trilokchand and Elaichi's Second son=younger brother of Amar.elder brother of Aayush,Ajay,Utpal,Avni,and Mishri.Chachu of Samar.Husband of Shreya.
• Sreejita De as Shreya Bhushan Pethewala=Wife of Bhushan Petewala.Chachi of Samar.
• Dimple Jhangiani as Avni Pethawala=Trilokchand and Elaichi's daughter=youngest sister of Amar,Bhushan,Aayush,Ajay,and Utpal.elder sister of Mishri.Bua of Samar.
• Lavina Tandon as Shaina=Fake Sister of Ajju.
• Madhu Malti Kapoor as Dadi=Mother of Trilokchand.Grandmother of Amar,Bhushan,Aayush,Ajay,Utpal,Avni,and Mishri.Great Grandmother of Samar.
• Tushar Dalvi as Trilokchand Pethawala=Son of Malti.Husband of Elaichi.Father of Amar,Bhushan,Ayush,Ajay,Utpal,Avni,and Mishri.GrandFather of Samar.
• Aishwarya Narkar as Elaichi Trilokchand Pethawala=Wife of Trilokchand.Mother of Amar,Bhushan,Ayush,Ajay,Utpal,Avni,and Mishri.GrandMother of Samar.
• Vineet Raina as Amar Pethawala=TrilokChand and Elaichi eldest son=eldest brother of Bhushan,Ayush,Ajay,Utpal,Avni,and Mishri.Husband of Vinati.father of Samar.
• Aalika Sheikh as Vinati Amar Pethawala=Wife of Amar Pethawala.Mother of Samar.
• Rehaan Khan as Samar Amar Pethawala=Amar and Vinati's son.niece of Bhushan,Ajay,Ayush,Utpal,Avni,and Mishri.
• Mahesh Tanwar as Utpal Trilokchand Pethawala=
• Ravjeet Singh as Aayush Pethawala
• Neha Dangal as Mishri Trilokchand Pethawala
• Neeraj Goswani as Ajju