Viomycin kinase

In enzymology, viomycin kinase (EC 2.7.1.103) is an enzyme that catalyzes the chemical reaction

ATP + viomycin ADP + O-phosphoviomycin
Viomycin kinase
Identifiers
EC no.2.7.1.103
CAS no.77000-11-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Thus, the two substrates of this enzyme are ATP and viomycin, whereas its two products are ADP and O-phosphoviomycin.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:viomycin O-phosphotransferase. Other names in common use include viomycin phosphotransferase, and capreomycin phosphotransferase.

References

    • Skinner RH, Cundliffe E (1980). "Resistance to the antibiotics viomycin and capreomycin in the Streptomyces species which produce them". J. Gen. Microbiol. 120 (1): 95–104. doi:10.1099/00221287-120-1-95. PMID 6163840.


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