WDHD1

WD repeat and HMG-box DNA binding protein 1 is a protein in humans that is encoded by the WDHD1 gene. [5]

WDHD1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesWDHD1, AND-1, CHTF4, CTF4, AND1, WD repeat and HMG-box DNA binding protein 1, Ctf4
External IDsOMIM: 608126 MGI: 2443514 HomoloGene: 56019 GeneCards: WDHD1
Orthologs
SpeciesHumanMouse
Entrez

11169

218973

Ensembl

ENSG00000198554

ENSMUSG00000037572

UniProt

O75717

P59328

RefSeq (mRNA)

NM_001008396
NM_007086

NM_172598
NM_001360532

RefSeq (protein)

NP_001008397
NP_009017

NP_766186
NP_001347461

Location (UCSC)Chr 14: 54.94 – 55.03 MbChr 14: 47.48 – 47.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

References

  1. GRCh38: Ensembl release 89: ENSG00000198554 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000037572 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: WD repeat and HMG-box DNA binding protein 1". Retrieved 2013-02-18.

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.