Zerumbone synthase

Zerumbone synthase (EC 1.1.1.326, ZSD1) is an enzyme with systematic name 10-hydroxy-alpha-humulene:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

10-hydroxy-alpha-humulene + NAD+ zerumbone + NADH + H+
Zerumbone synthase
Identifiers
EC no.1.1.1.326
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme was cloned from shampoo ginger, Zingiber zerumbet.

References

  1. Okamoto S, Yu F, Harada H, Okajima T, Hattan J, Misawa N, Utsumi R (August 2011). "A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet". The FEBS Journal. 278 (16): 2892–900. doi:10.1111/j.1742-4658.2011.08211.x. PMID 21668645.
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