Apolipoprotein C-IV

Apolipoprotein C-IV, also known as apolipoprotein C4, is a protein that in humans is encoded by the APOC4 gene.[5][6]

APOC4
Identifiers
AliasesAPOC4, APO-CIV, APOC-IV, apolipoprotein C4
External IDsOMIM: 600745 MGI: 87878 HomoloGene: 1245 GeneCards: APOC4
Orthologs
SpeciesHumanMouse
Entrez

346

11425

Ensembl

ENSG00000267467

ENSMUSG00000074336

UniProt

P55056

Q61268

RefSeq (mRNA)

NM_001646

NM_007385

RefSeq (protein)

NP_001637

NP_031411

Location (UCSC)Chr 19: 44.94 – 44.95 MbChr 7: 19.41 – 19.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

APOC4 is a member of the apolipoprotein C gene family. It is expressed in the liver and has a predicted protein structure characteristic of the other genes in this family. APOC4 is a 3.3-kb gene consisting of 3 exons and 2 introns; it is located 0.5 kb 5' to the APOC2 gene.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000267467 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000074336 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: apolipoprotein C-IV".
  6. Allan CM, Walker D, Segrest JP, Taylor JM (July 1995). "Identification and characterization of a new human gene (APOC4) in the apolipoprotein E, C-I, and C-II gene locus". Genomics. 28 (2): 291–300. doi:10.1006/geno.1995.1144. PMID 8530039.
  • Human APOC4 genome location and APOC4 gene details page in the UCSC Genome Browser.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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