Dextranomer

Dextranomer (trade name Debrisan, Exudex[1]) is a cicatrizant used in dressings for wound healing,[2] and in pharmaceutical products to treat fecal incontinence.[3] It consists of dextran polymer chains cross-linked into a three-dimensional network.[4]

Dextranomer
Clinical data
Trade namesDebrisan
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Topical
ATC code
Identifiers
IUPAC name
  • Dextran, 2,3-dihydroxypropyl 2-hydroxy-1,3-propanediyl ethers
CAS Number
PubChem SID
ChemSpider
  • none
UNII
ECHA InfoCard100.128.106
 NY (what is this?)  (verify)

Solesta

Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI).[5] This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal anal canal (i.e. above the level of the dentate line).

References
  1. "Establishment Registration & Device Listing".
  2. Parulkar BG, Sobti MK, Pardanani DS (1985). "Dextranomer dressing in the treatment of infected wounds and cutaneous ulcers". J Postgrad Med. 31 (1): 28–33. PMID 2413198.
  3. "Solesta Gel Approved for Fecal Incontinence - Drugs.com MedNews".
  4. Solesta Package Insert
  5. Hoy, SM (Aug 20, 2012). "Dextranomer in stabilized sodium hyaluronate (Solesta): in adults with faecal incontinence". Drugs. 72 (12): 1671–8. doi:10.2165/11209030-000000000-00000. PMID 22845415. S2CID 6499631.
  • dextranomer at the US National Library of Medicine Medical Subject Headings (MeSH)


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