Epsiprantel

Epsiprantel (trade name Cestex) is a veterinary drug which is used as an anthelmintic against tapeworms such as Echinococcus granulosus.[2]

Epsiprantel
Clinical data
Trade namesCestex
Other namesBRL 38705
Routes of
administration		By mouth (tablets)
ATCvet code
Legal status
Legal status
Pharmacokinetic data
BioavailabilityMinimal[1]
Identifiers
IUPAC name
  • 2-(Cyclohexylcarbonyl)-2,3,6,7,8,12b-hexahydropyrazino[2,1-a][2]benzazepin-4(1H)-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H26N2O2
Molar mass326.440 g·mol−1
3D model (JSmol)
SMILES
  • O=C4N2C(c1c(cccc1)CCC2)CN(C(=O)C3CCCCC3)C4
InChI
  • InChI=1S/C20H26N2O2/c23-19-14-21(20(24)16-8-2-1-3-9-16)13-18-17-11-5-4-7-15(17)10-6-12-22(18)19/h4-5,7,11,16,18H,1-3,6,8-10,12-14H2
  • Key:LGUDKOQUWIHXOV-UHFFFAOYSA-N

Indications

It is indicated for the removal of cestodes (tapeworms) in cats (Dipylidium caninum and Taenia taeniaeformis) and dogs (Dipylidium caninum and Taenia pisiformis) 7 weeks of age and older.[1]

References
  1. "Cestex (epsiprantel) Veterinary Tablets. Prescribing Information" (PDF). Zoetis Inc. Kalamazoo, MI 49007. Retrieved 2 October 2016.
  2. Arru E, Garippa G, Manger BR (November 1990). "Efficacy of epsiprantel against Echinococcus granulosus infections in dogs". Research in Veterinary Science. 49 (3): 378–9. doi:10.1016/0034-5288(90)90080-N. PMID 2267429.
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