Ciclobendazole

Ciclobendazole is an anthelmintic, that is a pharmaceutical drug against parasitic worms. It underwent a clinical trial in the 1970s, where it was found to be as effective as mebendazole in the treatment of hookworm infection and ascariasis, but significantly less effective in the treatment of trichuriasis.[1]

Ciclobendazole
Clinical data
ATC code
Identifiers
IUPAC name
  • Methyl N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.046.018
Chemical and physical data
FormulaC13H13N3O3
Molar mass259.265 g·mol−1
3D model (JSmol)
SMILES
  • COC(=O)Nc3nc2ccc(C(=O)C1CC1)cc2[nH]3
InChI
  • InChI=1S/C13H13N3O3/c1-19-13(18)16-12-14-9-5-4-8(6-10(9)15-12)11(17)7-2-3-7/h4-7H,2-3H2,1H3,(H2,14,15,16,18) N
  • Key:OXLKOMYHDYVIDM-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

It is not known to be marketed anywhere in the world.[2]

References
  1. Guggenmoos R, Akhtaruzzaman KM, Rosenkaimer F, Gaus W, Bienzle U, Dietrich M (December 1978). "Comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole". Tropenmedizin und Parasitologie. 29 (4): 423–6. PMID 369076.
  2. "Ciclobendazole search results". Drugs.com. Retrieved 2021-03-31.
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