Isolated growth hormone deficiency

Isolated growth hormone deficiency (IGHD) is a rare congenital disorder characterized by growth hormone deficiency and postnatal growth failure.[1][2] It is divided into four subtypes that vary in terms of cause and clinical presentation.[1][2] They include IGHD IA (autosomal recessive, absent GH), IGHD IB (autosomal recessive, diminished GH), IGHD II (autosomal dominant, diminished GH), and IGHD III (X-linked, diminished GH).[1][2]

References
  1. Ora Hirsch Pescovitz; Erica A. Eugster, eds. (2004). Pediatric Endocrinology: Mechanisms, Manifestations, and Management. Lippincott Williams & Wilkins. pp. 129–. ISBN 978-0-7817-4059-3. OCLC 1055331544.
  2. Jurado, Pérez; Argente, J. (1994). "Molecular Basis of Familial Growth Hormone Deficiency". Hormone Research. 42 (4–5): 189–197. doi:10.1159/000184192. eISSN 1423-0046. ISSN 0301-0163. PMID 7868072.


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