Leishmania tropica
Leishmania tropica is a species of flagellate parasites that infects humans and hyraxes, and the cause of the disease Leishmaniasis Recidivans, a form of cutaneous leishmaniasis.[1] L. tropica infection results in non-ulcerating disease.
| Leishmania tropica | |
|---|---|
 | |
| Promastigotes of Leishmania tropica. Giemsa stain, 10×100. | |
Scientific classification  | |
| Domain: | Eukaryota |
| Phylum: | Euglenozoa |
| Class: | Kinetoplastea |
| Order: | Trypanosomatida |
| Genus: | Leishmania |
| Species: | L. tropica |
| Binomial name | |
| Leishmania tropica Wright, 1903 | |
Fusion and hybridization of different L. tropica strains can be efficiently induced in vitro by exposure of promastigotes (a stage of the life cycle) to DNA damage stress.[2] The fused cells do not undergo meiosis and are mostly tetraploid.
Cutaneous leishmaniasis in North Africa; Leishmania tropica infected areas are in red[3]
References
- Gitari JW, Nzou SM, Wamunyokoli F, Kinyeru E, Fujii Y, Kaneko S, Mwau M (2018). "Leishmaniasis recidivans by Leishmania tropica in Central Rift Valley Region in Kenya". Int J Infect Dis. 74: 109–116. doi:10.1016/j.ijid.2018.07.008. PMID 30017946.
- Louradour I, Ferreira TR, Duge E, Karunaweera N, Paun A, Sacks D. Stress conditions promote Leishmania hybridization in vitro marked by expression of the ancestral gamete fusogen HAP2 as revealed by single-cell RNA-seq. Elife. 2022;11:e73488. Published 2022 Jan 7. doi:10.7554/eLife.73488
- Aoun, K.; Bouratbine, A. (2014). "Cutaneous Leishmaniasis in North Africa: a review". Parasite. 21: 14. doi:10.1051/parasite/2014014. PMC 3952656. PMID 24626301.
Further reading
- Saroufim, Maya; Charafeddine, Khalil; Issa, Grace (October 2014). "Ongoing Epidemic of Cutaneous Leishmaniasis among Syrian Refugees, Lebanon". Emerging Infectious Diseases. 20 (10): 1712–1715. doi:10.3201/eid2010.140288. PMC 4193275. PMID 25279543.
- Solomon, Michal; Schwartz, Eli; Pavlotsky, Felix (Aug 2014). "Leishmania tropica in children: A retrospective study". Journal of the American Academy of Dermatology. 71 (2): 271–7. doi:10.1016/j.jaad.2013.12.047. PMID 24775403.
- Krayter, Lena; Alam, Mohammad Zahangir; Rhajaoui, Mohamed; Schnur, Lionel F. (December 2014). "Multilocus Microsatellite Typing reveals intra-focal genetic diversity among strains of Leishmania tropica in Chichaoua Province, Morocco". Infection, Genetics and Evolution. 28: 233–239. doi:10.1016/j.meegid.2014.09.037.
- Hammoudeh, Nour; Kweider, Mahmoud; Abbady, Abdul-Qader; Soukkarieh, Chadi (Oct 2014). "Sequencing and Gene Expression Analysis of Leishmania tropica LACK Gene" (PDF). Iranian J Parasitol. 9 (4): 574–583. PMC 4345098. PMID 25759740. Retrieved 9 February 2015.
- Mahmoudzadeh-Niknam H, Kiaei SS, Iravani D (2007). "Leishmania tropica infection, in comparison to Leishmania major, induces lower delayed type hypersensitivity in BALB/c mice". Korean J Parasitol. 45 (2): 103–9. doi:10.3347/kjp.2007.45.2.103. PMC 2526302. PMID 17570972.
External links
Media related to Leishmania tropica at Wikimedia Commons- US Center for Disease Control and Prevention. Leishmaniasis – General Information
- Cancer Web
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