Mean glandular dose

Mean glandular dose (MGD) is a quantity used to describe the absorbed dose of radiation to the breast in mammography. It is based on a measurement of air kerma and conversion factors. MGD can be calculated from measurements made with PMMA blocks. It is often used to compare typical doses to patients between different centres or internationally, and is the preferred measure of the potential risk from mammography.[1][2][3]

Calculation

MGD can be calculated from a measured incident air kerma at the top of the breast, , as follows:[4]

converts from incident air kerma to MGD, with a glandularity of 50%, based on breast thickness and HVL. corrects for glandularity other than 50%, depending on the breast thickness and HVL, with two versions for ages 50–64 and 40–49. corrects for the x-ray spectra in use with a table of target/filter combinations.[4][5]

Applications

MGD is typically used to define limits on mammography exposures by national and international organisations such as the European Union and International Atomic Energy Agency, at <2.5 milligray (mGy) per exposure to a standard breast (4.5 cm PMMA).[6]

In routine quality assurance testing of mammographic equipment, MGD measurements for a range of effective breast thicknesses with PMMA, and from real patient exposures, is widely recommended.[2]

References
  1. Yaffe, Marlin J.; Barnes, Gary T.; Conway, Burton J.; Haus, Arthur G.; Karellas, Andrew; Kimme-Smith, Carolyn; Paul Lin, Pei-Jan; Mawdsley, Gordon; Rauch, Phillip; Rothenberg, Lawrence N. (1990). Equipment requirements and quality control for mammography. New York, NY: American Association of Physics in Medicine. ISBN 978-0-883188-07-1.
  2. Reis, Cláudia; Pascoal, Ana; Sakellaris, Taxiarchis; Koutalonis, Manthos (4 August 2013). "Quality assurance and quality control in mammography: a review of available guidance worldwide". Insights into Imaging. 4 (5): 539–553. doi:10.1007/s13244-013-0269-1. PMC 3781250. PMID 23912879.
  3. "Quality assurance guidelines for mammography including radiographic quality control". Public Health England. 2006.
  4. IAEA (2011). Quality assurance programme for digital mammography. Vienna: International Atomic Energy Agency. ISBN 978-92-0-111410-5.
  5. Dance, D R; Skinner, C L; Young, K C; Beckett, J R; Kotre, C J (1 November 2000). "Additional factors for the estimation of mean glandular breast dose using the UK mammography dosimetry protocol". Physics in Medicine and Biology. 45 (11): 3225–3240. Bibcode:2000PMB....45.3225D. doi:10.1088/0031-9155/45/11/308. PMID 11098900.
  6. Health & Consumer Protection, Directorate-General (2006). Perry, N (ed.). European guidelines for quality assurance in breast cancer screening and diagnosis (4th ed.). Luxembourg: Office for Official Publ. of the Europ. Communities. p. 203. ISBN 978-92-79-01258-7.
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