Pristinamycin IIB

Pristinamycin IIB is an antibiotic of the streptogramin A class. It was isolated from Streptomyces pristinaespiralis[1] and its chemical structure was first determined in 1966.[2]

Pristinamycin IIB
Names
Other names
(27R)-26,27-Dihydrovirginiamycin M1; Ostreogrycin G; Virginiamycin M2; Volpristin
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.132.888
PubChem CID
UNII
InChI
  • InChI=1S/C28H37N3O7/c1-17(2)26-19(4)7-8-24(34)29-10-5-6-18(3)12-21(32)13-22(33)14-25-30-23(16-37-25)27(35)31-11-9-20(15-31)28(36)38-26/h5-8,12,16-17,19-21,26,32H,9-11,13-15H2,1-4H3,(H,29,34)/b6-5+,8-7+,18-12+/t19-,20+,21-,26-/m1/s1
    Key: WMKFEQGQMBSGSA-TXZFEVTPSA-N
SMILES
  • O[C@H](/C=C(C)/C=C/CNC(/C=C/[C@@H](C)[C@H](OC1=O)C(C)C)=O)CC(CC2=NC(C(N3[C@@H]1CCC3)=O)=CO2)=O
Properties
Chemical formula
 C28H37N3O7
Molar mass 527.618 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References
  1. Preud'Homme, J; Tarridec, P; Belloc, A (1968). "90. Isolation, characterization and identification of the components of pristinamycin". Bulletin de la Société Chimique de France. 2: 585–91. PMID 5650822.
  2. Kingston, D. G.; Sarin, P. S.; Todd, L; Williams, D. H. (1966). "Antibiotics of the ostreogrycin complex. IV. The structure of ostreogrycin G". Journal of the Chemical Society, Perkin Transactions 1. 20: 1856–60. PMID 5950473.


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