United Kingdom Model for End-Stage Liver Disease

The United Kingdom Model for End-Stage Liver Disease or UKELD is a medical scoring system used to predict the prognosis of patients with chronic liver disease. It is used in the United Kingdom to help determine the need for liver transplantation.[1] It was developed from the MELD score, incorporating the serum sodium level.[2]

Determination

The UKELD score is calculated from the patient's INR, serum creatinine, serum bilirubin and serum sodium, according to the formula:[3]

Interpretation

Higher UKELD scores equate to higher one-year mortality risk. A UKELD score of 49 indicates a 9% one-year risk of mortality, and is the minimum score required to be added to the liver transplant waiting list in the U.K.[1] A UKELD score of 60 indicates a 50% chance of one-year survival.[2]

History

The UKELD score was developed in 2008 to aid in the selection of patients for liver transplantation in the U.K.[4]

See also

References
  1. "Liver Transplant - Who can use it - NHS Choices". NHS.uk. 2011-11-09. Retrieved 2013-01-20.
  2. Asrani SK, Kim WR (May 2010). "Organ allocation for chronic liver disease: model for end-stage liver disease and beyond". Curr. Opin. Gastroenterol. 26 (3): 209–13. doi:10.1097/MOG.0b013e32833867d8. PMC 2919807. PMID 20224394.
  3. Evangelos Cholongitas; Giacomo Germani; Andrew K. Burroughs (December 2010). "Prioritization for liver transplantation (Table 2)". Nature Reviews Gastroenterology & Hepatology. Nature Publishing Group. 7 (12): 659–668. doi:10.1038/nrgastro.2010.169. PMID 21045793. S2CID 6211258.
  4. Neuberger J, Gimson A, Davies M, et al. (February 2008). "Selection of patients for liver transplantation and allocation of donated livers in the UK". Gut. 57 (2): 252–7. doi:10.1136/gut.2007.131730. PMID 17895356. S2CID 35531839.
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