Xibornol

Xibornol is an antibiotic.

Xibornol
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 4,5-dimethyl-2-[(1S,4R,6R)-1,7,7-trimethyl-6-bicyclo[2.2.1]heptanyl]phenol
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.033.906
Chemical and physical data
FormulaC18H26O
Molar mass258.405 g·mol−1
3D model (JSmol)
SMILES
  • Oc1cc(c(cc1C2CC3CCC2(C)C3(C)C)C)C
InChI
  • InChI=1S/C18H26O/c1-11-8-14(16(19)9-12(11)2)15-10-13-6-7-18(15,5)17(13,3)4/h8-9,13,15,19H,6-7,10H2,1-5H3 Y
  • Key:RNRHMQWZFJXKLZ-UHFFFAOYSA-N Y
  (verify)

Overview

It is primarily administered to the throat.[1]

Xibornol is a lipophilic drug mainly used in Italy and Spain in spray dosage forms for the local treatment of infection and inflammation of the throat. Its poor water solubility makes difficult the development of aqueous formulations of the drug, thus giving rise to a limited number of stable and pharmaceutically accepted preparations. In fact, xibornol is actually marketed only as spray aqueous suspension.

References
  1. Cirri M, Mura P, Mora PC (2007). "Liquid spray formulations of xibornol by using self-microemulsifying drug delivery systems". Int J Pharm. 340 (1–2): 84–91. doi:10.1016/j.ijpharm.2007.03.021. PMID 17531411.


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