SS18

Synovial sarcoma translocation, chromosome 18
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB
Identificadores
Símbolos	SS18 (HGNC: 11340) MGC116875; SSXT; SYT
Identificadores; externos	OMIM: 600192 ; EBI: SS18; GeneCards: Gen SS18; UniProt: SS18;
Locus	Cr. 18 q11.2
	Referencias: AmiGO / QuickGO
Ortólogos
Humano	Ratón
6760
Q15532	n/a
NP_001007560	n/a

La proteína SSXT (SS18) es una proteína codificada en humanos por el gen SS18.[1][2][3][4]

Interacciones

La proteína SS18 ha demostrado ser capaz de interaccionar con:

Referencias

Shipley JM, Clark J, Crew AJ, Birdsall S, Rocques PJ, Gill S, Chelly J, Monaco AP, Abe S, Gusterson BA, et al. (mayo de 1994). «The t(X;18)(p11.2;q11.2) translocation found in human synovial sarcomas involves two distinct loci on the X chromosome». Oncogene 9 (5): 1447-53. PMID 8152806.
Clark J, Rocques PJ, Crew AJ, Gill S, Shipley J, Chan AM, Gusterson BA, Cooper CS (Dec de 1994). «Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma». Nat Genet 7 (4): 502-8. PMID 7951320. doi:10.1038/ng0894-502.
de Bruijn DR, Geurts van Kessel A (Feb de 2006). «Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci». Cytogenet Genome Res 112 (3-4): 222-6. PMID 16484776. doi:10.1159/000089874.
«Entrez Gene: SS18 synovial sarcoma translocation, chromosome 18».
de Bruijn, D R; dos Santos N R, Thijssen J, Balemans M, Debernardi S, Linder B, Young B D, Geurts van Kessel A (mayo. de 2001). «The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10». Oncogene (England) 20 (25): 3281-9. ISSN 0950-9232. PMID 11423977. doi:10.1038/sj.onc.1204419.
Eid, J E; Kung A L, Scully R, Livingston D M (Sep. de 2000). «p300 interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion». Cell (UNITED STATES) 102 (6): 839-48. ISSN 0092-8674. PMID 11030627.
Kato, Hiroyuki; Tjernberg Agneta, Zhang Wenzhu, Krutchinsky Andrew N, An Woojin, Takeuchi Tamotsu, Ohtsuki Yuji, Sugano Sumio, de Bruijn Diederik R, Chait Brian T, Roeder Robert G (Feb. de 2002). «SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones». J. Biol. Chem. (United States) 277 (7): 5498-505. ISSN 0021-9258. PMID 11734557. doi:10.1074/jbc.M108702200.
Perani, Michela; Ingram Catherine J E, Cooper Colin S, Garrett Michelle D, Goodwin Graham H (Nov. de 2003). «Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers». Oncogene (England) 22 (50): 8156-67. ISSN 0950-9232. PMID 14603256. doi:10.1038/sj.onc.1207031.

Datos: Q18031739

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[pmid8152806-1] Shipley JM, Clark J, Crew AJ, Birdsall S, Rocques PJ, Gill S, Chelly J, Monaco AP, Abe S, Gusterson BA, et al. (mayo de 1994). «The t(X;18)(p11.2;q11.2) translocation found in human synovial sarcomas involves two distinct loci on the X chromosome». Oncogene 9 (5): 1447-53. PMID 8152806.

[pmid7951320-2] Clark J, Rocques PJ, Crew AJ, Gill S, Shipley J, Chan AM, Gusterson BA, Cooper CS (Dec de 1994). «Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma». Nat Genet 7 (4): 502-8. PMID 7951320. doi:10.1038/ng0894-502.

[pmid16484776-3] Bruijn DR, Geurts van Kessel A (Feb de 2006). «Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci». Cytogenet Genome Res 112 (3-4): 222-6. PMID 16484776. doi:10.1159/000089874.

[entrez-4] «Entrez Gene: SS18 synovial sarcoma translocation, chromosome 18».

[pmid11423977-5] Bruijn, D R; dos Santos N R, Thijssen J, Balemans M, Debernardi S, Linder B, Young B D, Geurts van Kessel A (mayo. de 2001). «The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10». Oncogene (England) 20 (25): 3281-9. ISSN 0950-9232. PMID 11423977. doi:10.1038/sj.onc.1204419.

[pmid11030627-6] Eid, J E; Kung A L, Scully R, Livingston D M (Sep. de 2000). «p300 interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion». Cell (UNITED STATES) 102 (6): 839-48. ISSN 0092-8674. PMID 11030627.

[pmid11734557-7] Kato, Hiroyuki; Tjernberg Agneta, Zhang Wenzhu, Krutchinsky Andrew N, An Woojin, Takeuchi Tamotsu, Ohtsuki Yuji, Sugano Sumio, de Bruijn Diederik R, Chait Brian T, Roeder Robert G (Feb. de 2002). «SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones». J. Biol. Chem. (United States) 277 (7): 5498-505. ISSN 0021-9258. PMID 11734557. doi:10.1074/jbc.M108702200.

[pmid14603256-8] Perani, Michela; Ingram Catherine J E, Cooper Colin S, Garrett Michelle D, Goodwin Graham H (Nov. de 2003). «Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers». Oncogene (England) 22 (50): 8156-67. ISSN 0950-9232. PMID 14603256. doi:10.1038/sj.onc.1207031.