Examples of course of antibiotics in the following topics:
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- In uncomplicated cases, a diagnosis may be made and treatment given based on symptoms alone without further laboratory confirmation, and treatment involves a short course of antibiotics such as nitrofurantoin or trimethoprim / sulfamethoxazole.
- A longer course or intravenous antibiotics may be needed.
- In those with frequent infections, a short course of antibiotics may be taken as soon as symptoms begin or long term antibiotics may be used as a preventative measure.
- For those with recurrent infections, taking a short course of antibiotics when each infection occurs is associated with the lowest antibiotic use.
- A prolonged course of daily antibiotics is also effective.
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- Antibiotic misuse is one factor responsible for the emergence of antimicrobial resistant bacterial strains.
- With the introduction of antibiotics into medical practice, clinically-relevant bacteria have had to adopt resistance mechanisms as part of their survival strategy.
- Developing new antibiotics and other treatments to keep pace with antibiotic-resistant strains of bacteria is necessary.
- Antibiotic misuse has contributed largely to the emergence of new resistant strains.
- It can also be manifested by not finishing a course of antibiotics as prescribed (stopping the antibiotic before the infection is fully cleared from the body).
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- The antibiotics of choice should be bactericidal (e.g., quinolone) not bacteriostatic (e.g., tetracycline) if the infection is life-threatening.
- Treatment of chronic prostatitis requires courses of antibiotic administration for one to two months or a longer course with low doses.
- In these cases higher success rates of treatment are achieved when a combination of antibiotics is used.
- The choice of antibiotic for chronic prostatitis also depends on its ability to penetrate the prostatic capsule.
- In the case of acute prostatitis, the prostate-blood barrier is damaged by the infection so the penetrating ability of the antibiotic is not as important.
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- The era of antimicrobials begins when Pasteur and Joubert discover that one type of bacteria could prevent the growth of another.
- They did not know at that time that the reason one bacterium failed to grow was that the other bacterium was producing an antibiotic.
- Technically, antibiotics are only those substances that are produced by one microorganism that kill, or prevent the growth, of another microorganism.
- Now, most of these infections can be cured easily with a short course of antimicrobials.
- The term antibiotic was first used in 1942 by Selman Waksman and his collaborators in journal articles to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution.
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- Antimycobacterial antibiotics are a class of antimicrobial drugs that target mycobacterium.
- Antiomycobacterial antibiotics specifically target these types of microbes.
- A type of antimycobacterial antibiotic includes the class of drugs used for tuberculosis (TB) treatment.
- The use of multidrug therapies including dapsone, clofazimine and rifampicin were advantageous due to the low risk of antibiotic resistance.
- Antimycobacterial antibiotics target mycobacterium.
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- Both of these closely related antibiotics have similar levels efficacy, although doxycycline has a slightly lower risk of adverse side effects.
- Antibiotics can be divided into two classes based on their mechanism of action.
- Bacteriostatic antibiotics limit the growth of bacteria by interfering with bacterial protein production, DNA replication, or other aspects of bacterial cellular metabolism.
- "Narrow-spectrum" antibacterial antibiotics target specific types of bacteria, such as Gram-negative or Gram-positive bacteria, whereas broad-spectrum antibiotics affect a wide range of bacteria, usually both gram positive and gram negative cells.
- Tetracycline antibiotics are protein synthesis inhibitors, inhibiting the binding of aminoacyl-tRNA to the mRNA-ribosome complex.
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- Kirby-Bauer testing measures sensitivity of bacteria to antibiotics by culturing bacteria on solid growth media surrounding sources of drug.
- Then, a known quantity of bacteria are grown overnight on agar (solid growth media) plates in the presence of a thin wafer that contains a known amount of a relevant antibiotic.
- A larger zone of inhibition around an antibiotic-containing disk indicates that the bacteria are more sensitive to the antibiotic in the disk.
- If the observed zone of inhibition is greater than or equal to the size of the standard zone, the microorganism is considered to be sensitive to the antibiotic.
- The size of a zone of inhibition in a KB test is inversely related to the minimum inhibitory concentration (MIC), which is the amount of antibiotic required to prevent bacterial growth in an overnight culture.
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- In observational studies, nature is allowed to "take its course", as epidemiologists observe from the sidelines.
- This strategy might be used to test whether or not a particular antibiotic is effective against a particular disease-causing organism.
- One group of infected individuals is divided randomly so that some receive the antibiotic and others receive a placebo—a "false" drug that is not known to have any medical effect.
- If people in the group receiving the antibiotic recover more rapidly than those in the other group, it may logically be concluded that the variable—antibiotic treatment—made the difference.
- Thus, the antibiotic is said to be effective.
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- Biotechnological advances in gene manipulation techniques have further resulted in the production of vaccines, antibiotics, and hormones.
- Antibiotics are biotechnological products that inhibit bacterial growth or kill bacteria.
- Antibiotics are produced on a large scale by cultivating and manipulating fungal cells.
- Assays such as the one shown help scientists understand the effects of antibiotics on bacterial species.
- Discuss the methods by which biotechnology is used to produce vaccines, antibiotics, and hormones.