creatinine
(noun)
A heterocyclic amine 2-amino-1-methyl-5H-imidazol-4-one formed by the metabolism of creatine.
Examples of creatinine in the following topics:
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Renal Disease and Failure
- Renal failure uremia is a syndrome of renal failure characterized by elevated levels of urea and creatinine in the blood.
- This is detected by a decrease in or absence of urine production or determination of waste products (creatinine or urea) in the blood.
- Renal failure can be divided into two categories: acute kidney injury or chronic kidney disease .The type of renal failure is determined by the trend in the serum creatinine.
- Renal failure uremia is a syndrome of renal failure that includes elevated blood urea and creatinine levels.
- Diagnostic tests include BUN and plasma creatinine level tests.
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Tubular Secretion
- Hydrogen, creatinine, and drugs are removed from the blood and into the collecting duct through the peritubular capillary network.
- At this final stage it is only approximately one percent of the originally filtered volume, consisting mostly of water with highly diluted amounts of urea, creatinine, and variable concentrations of ions.
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Chemical Composition of Urine
- The normal chemical composition of urine is mainly water content, but it also includes nitrogenous molecules, such as urea, as well as creatinine and other metabolic waste components.
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Edema Caused by Loss of Plasma Proteins
- Microalbuminuria between 30 and 300 mg/24h, mg/l of urine or µg/mg of creatinine can be a forerunner of diabetic nephropathy.
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Diagnostic Blood Tests
- A basic metabolic panel measures sodium, potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes includes calcium.
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Pulmonary Edema
- Blood tests are performed for electrolytes (sodium, potassium) and markers of renal function (creatinine, urea).
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Overview of Urine Formation
- During secretion some substances±such as hydrogen ions, creatinine, and drugs—will be removed from the blood through the peritubular capillary network into the collecting duct.
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Acidosis
- Renal acidosis is associated with an accumulation of urea and creatinine as well as metabolic acid residues of protein catabolism.
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Dialysis
- The counter-current flow of the blood and dialysate maximizes the concentration gradient of solutes between the blood and dialysate, which helps to remove more urea and creatinine from the blood.
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Placenta
- Waste products excreted from the fetus—urea, uric acid, and creatinine—are transferred to the maternal blood by diffusion across the placenta.