Examples of Pinkerton agents in the following topics:
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- The Molly Maguires were an Irish-American organization of coal miners, opposed and persecuted by industrialists and Pinkerton agents.
- In the 1870s, the Reading Railroad blamed the deals of two dozen mine foremen and administrators on a secret society of Irishmen called the "Molly Maguires. " Although the Reading Railroad hired a Pinkerton undercover detective to investigate, it is highly probable that most of the men accused and executed for being Molly Maguires were innocent.
- Gowen and the testimony of Pinkerton detective James McParland.
- Gowen decided to force a strike and showdown, and hired Pinkerton agent James McParland to go undercover against the Mollies.
- McParland's assignment was to collect evidence of murder plots and intrigue, passing this information along to his Pinkerton manager.
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- After three agents were shot, many of the Pinkertons refused to continue the firefight.
- Just before noon, a sniper shot killed another Pinkerton agent.
- The Pinkertons, too, wished to surrender.
- Their arms were stripped from them, and as the Pinkertons crossed the grounds of the mill, the crowd formed a gauntlet through which the agents passed.
- Men and women threw sand and stones at the Pinkerton agents, spat on them, and beat them.
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- Industrialist Henry Clay Frick sent private security agents from the Pinkerton National Detective Agency to break the Amalgamated Association of Iron and Steel Workers strike at a Homestead, Pennsylvania steel mill.
- Two strikers were killed, 12 wounded, along with 2 Pinkertons killed and 11 wounded.
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- The principle-agent problem (agency dilemma) exists when conflicts of interest arise between a principal and an agent in a business setting.
- In economics, the principal-agent problem (also known as an agency dilemma) exists when conflicts of interest arise between a principal and an agent in a business setting .
- This connection sets the standard for judging the performance of the agent.
- The diagram shows the basic idea of the principle agent problem.
- P is the principle and A is the agent.
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- Pinkerton, Richard L. (1994).
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- Those that result in bacterial death are called bactericidal agents.
- Those causing temporary inhibition of growth are bacteriostatic agents.
- No single antimicrobial agent is most effective for use in all situations - different situations may call for different agents.
- A number of factors affect selection of the best agent for any given situation - Antimicrobial agents must be selected with specific organisms and environmental conditions in mind.
- Once an agent has been selected, it is important to evaluate it's effectiveness.
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- A decision also implies the existence of an agent.
- In the case of an agent or agents representing a principal, there may be a conflict or incompatibility among their objectives.
- This is referred to as the principal/agent problem.
- The agent has a conflict of interest.
- A stockbroker acts as an agent for an investor; a doctor may act as the agent for a patient.
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- Antisense agents are short oligonucleotides that bind to target messenger RNA and inhibit protein synthesis.
- When this agent binds to the pathogen DNA or messenger RNA, the biosynthesis of target proteins is disrupted.
- A limiting factor in their potential application as therapeutic agents for bacterial infections is their poor uptake by bacterial cells.
- Antisense agents also exhibit efficacy in broader clinical applications such as cancer therapy.
- Discuss the mechanism of antisense agents and the advantages and disadvantages of antisense therapy
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- Note that Lithium Aluminum Hydride (LiAlH4) is the strongest reducing agent listed, and it reduces all the substrates.
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- Usually these ligands are organic compounds and are called chelants, chelators, chelating agents, or sequestering agents; the resulting complexes are called chelate compounds.
- Chelation therapy is the use of chelating agents to detoxify poisonous metal agents, such as mercury, arsenic, and lead, by converting them to a chemically inert form that can be excreted without further interaction with the body.
- Such chelating agents include the porphyrin rings in hemoglobin and chlorophyll.
- Enterobactin, produced by E. coli, is the strongest chelating agent known.
- Ethylenediamine serves as a chelating agent by binding via its two nitrogen atoms.