Examples of reporter gene in the following topics:
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- In molecular biology, researchers use a reporter gene that they attach to a regulatory gene of interest.
- Reporter genes ideally have distinguishable properties that can be easily detected and measured.
- To introduce a reporter gene into an organism, scientists place the reporter gene and the gene of interest in the same DNA construct to be inserted into the cell or organism.
- It is important to use a reporter gene that is not natively expressed in the cell or organism under study, since the expression of the reporter is being used as a marker for successful uptake of the gene of interest.
- Reporter gene used as an indication of the regulatory sequence expression in the cell.
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- A reporter fusion is the hybrid of a gene or portion of a gene with a tractable marker.
- In molecular biology, a reporter gene (often simply reporter) is a gene that researchers attach to a regulatory sequence of another gene of interest in bacteria, cell culture, animals, or plants .
- To introduce a reporter gene into an organism, scientists place the reporter gene and the gene of interest in the same DNA construct to be inserted into the cell or organism.
- In these cases the reporter is directly attached to the gene of interest to create a gene fusion.
- In molecular biology, a reporter gene (often simply reporter) is a gene that researchers attach to a regulatory sequence of another gene of interest in bacteria, cell culture, animals, or plants
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- In July of 2011, Gene Munster of Piper Jaffray reported the results of a survey in a note to clients.
- This research was reported throughout the media.
- But has this report understated the importance of the study?
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- It is estimated to contain only 537 protein-encoding genes.
- Notably, the latter virus has the largest currently reported ssDNA genome.
- Defenses against these viruses may involve RNA interference from repetitive DNA sequences that are related to the genes of the viruses.
- Other characteristic archaean features are the organization of genes of related function—such as enzymes that catalyze steps in the same metabolic pathway into novel operons, and large differences in tRNA genes and their aminoacyl tRNA synthetases.
- Post-transcriptional modification is simpler than in eukaryotes, since most archaean genes lack introns, although there are many introns in their transfer RNA and ribosomal RNA genes, and introns may occur in a few protein-encoding genes.
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- Gene families are groups of functionally related genes arising from a duplicated gene.
- A gene family is a set of several similar genes, formed by duplication of a single original gene, that generally have similar biochemical functions .
- If the genes of a gene family encode proteins, the term protein family is often used in an analogous manner to gene family.
- In contrast, gene complexes are simply tightly linked groups of genes, often created via gene duplication (sometimes called segmental duplication if the duplicates remain side-by-side).
- Unequal crossing over generates gene families.
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- As mentioned, under normal circumstances intelligence involves multiple genes.
- However, certain single-gene genetic disorders can severely affect intelligence.
- While experts believe the genetic cause for Down syndrome is a lack of genes in the 21st chromosome, the gene(s) responsible for the cognitive symptoms have yet to be discovered.
- A group of largely African American, urban first-grade children and their caregivers were evaluated using self-report, interview, and standardized tests, including IQ tests.
- The study reported that exposure to violence and trauma-related distress in young children was associated with substantial decreases in IQ and reading achievement.
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- The B gene controls black (B_) vs. brown (bb) color, while the E gene controls yellow (ee) color.
- Genes may also oppose each other with one gene modifying the expression of another.
- Often the biochemical basis of epistasis is a gene pathway in which the expression of one gene is dependent on the function of a gene that precedes or follows it in the pathway.
- In this case, the C gene is epistatic to the A gene.
- Thus, the C gene is epistatic to the A gene.
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- Cancer, a disease of altered gene expression, is the result of gene mutations or dramatic changes in gene regulation.
- Cancer can be described as a disease of altered gene expression.
- There are many proteins that are turned on or off (gene activation or gene silencing) that dramatically alter the overall activity of the cell.
- This can be the result of gene mutation or changes in gene regulation (epigenetic, transcription, post-transcription, translation, or post-translation).
- It can bind to sites in the promoters of genes to initiate transcription.
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- Mendel said that factors, later called genes, normally occur in pairs in ordinary body cells, yet segregate during the formation of sex cells.
- The dominant gene, such as the purple flower in Mendel's plants, will hide the recessive gene, the white flower.
- The upshot is that Mendel observed the presence of chance in relation to which gene-pairs a seed would get.
- Because the number of pollen grains is large in comparison to the number of seeds, the selection of gene-pairs is essentially independent.
- It is also possible that Mendel's results were "too good" merely because he reported the best subset of his data — Mendel mentioned in his paper that the data was from a subset of his experiments.
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- Silencing genes through epigenetic mechanisms is very common in cancer cells and include modifications to histone proteins and DNA that are associated with silenced genes.
- When these modifications occur, the gene present in that chromosomal region is silenced.
- In cancer cells, silencing genes through epigenetic mechanisms is a common occurrence.
- Mechanisms can include modifications to histone proteins and DNA associated with these silencing genes.
- Describe the role played by epigenetic alterations to gene expression in the development of cancer