Case #279 - July, 2010
While examining a malaria-positive smear on a patient from Uganda, microbiologists at the Ontario Agency for Health Protection and Promotion observed what they believed to be a microfilaria. Images were captured and sent via email to the DPDx Team for diagnostic assistance. Figure A shows the object of interest, which measured approximately 200 micrometers in length. Figures B and C show close-ups of the anterior and posterior ends, respectively. What is your diagnosis? Based on what criteria?
Figure A
Figure B
Figure C
Case Answer
This was a case of perstans filariasis caused by Mansonella perstans. Diagnostic morphologic features included:
- an unsheathed microfilaria within the size range for the species (190-200 micrometers in length).
- a compact column of nuclei.
- a blunt tail that contains nuclei to the end of the tail (Figure C).
More on: Mansonellosis
Images presented in the monthly case studies are from specimens submitted for diagnosis or archiving. On rare occasions, clinical histories given may be partly fictitious.
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