Case #347 - May, 2013
Random night blood specimens were collected from over 500 subjects in an area endemic for lymphatic filariasis in coastal India. Roughly one-third of the cases were symptomatic, with or without recurrent episodes of fever and various degrees of lymphedema. The objects in Figures A and B were observed on Giemsa-stained thick blood films from several of the asymptomatic cases. The objects measured on average 220 micrometers in length. What is your diagnosis? Based on what criteria?
Figure A
Figure B
Case Answer
This was a case of lymphatic filariasis caused by Brugia malayi. Diagnostic morphologic features included:
- sheathed microfilaria within the size range for B. malayi.
- dense nuclear column in which individual nuclei are easily defined.
- microfilariae with a relatively long head space and a tail with terminal and subterminal nuclei.
More on: Lymphatic Filariasis
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